Ethyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate

CAS: 18585-06-3

Rif. TR-E903625

Informazioni sul prodotto

• Nome: Ethyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate
• Sinonimi: N-[4-Chloro-3-(trifluoromethyl)phenyl]carbamic Acid Ethyl Ester, [4-Chloro-3-(trifluoromethyl)phenyl]carbamic Acid Ethyl Ester, 4-Chloro-3-(trifluoromethyl)carbanilic Acid Ethyl Ester, Sorafenib Impurity 2
• Marchio: TRC
• Descrizione: Applications Ethyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.References Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)

Proprietà chimiche

• Peso molecolare: 267.63
• Formula: C₁₀H₉ClF₃NO₂
• Colore/Forma: Neat
• InChI: InChI=1S/C10H9ClF3NO2/c1-2-17-9(16)15-6-3-4-8(11)7(5-6)10(12,13)14/h3-5H,2H2,1H3,(H,15,16)
• InChI key: InChIKey=BAFPGGUKCVCSKG-UHFFFAOYSA-N
• SMILES: CCOC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1