9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one

CAS: 1486466-31-2

Rif. TR-F591800

Informazioni sul prodotto

• Nome: 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
• Sinonimi: Clobetasol Propionate 17alpha-spiro Compound, 9a-Fluoro-11b-hydroxy-16b-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one,(17R)-4'-Chloro-5'-ethyl-9-fluoro-11ß-hydroxy-16ß-methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione, Clobetasol Propionate 17a-spiro Compound, (17R)-4'-Chloro-5'-ethyl-9-fluoro-11beta-hydroxy-16beta-methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione, USP Clobetasol propionate Related Compound A, Ph Eur Clobetasol Propionate Impurity J, CCI18747, CCI6990, Clobetasol-17-propionate, CCI1822, Clobetasol-17-propionate isomer, 21-desoxybetamethasone-17-propionate, 16-ene, Ethylenic acid, USP Clobetasol propionate Related Compound A

Descrizione

Impurity Clobetasol Propionate EP Impurity J
Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.
References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 448.95
• Formula: C₂₅H₃₀ClFO₄
• Colore/Forma: Neat
• InChI: InChI=1S/C25H30ClFO4/c1-5-18-20(26)21(30)25(31-18)13(2)10-17-16-7-6-14-11-15(28)8-9-22(14,3)24(16,27)19(29)12-23(17,25)4/h8-9,11,13,16-17,19,29H,5-7,10,12H2,1-4H3/t13-,16-,17-,19-,22-,23-,24-,25-/m0/s1
• InChI key: InChIKey=LXZPFTQONPQBQD-TUZVJILZSA-N
• SMILES: CCC1=C(Cl)C(=O)[C@@]2(O1)[C@@H](C)C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]12C