GW 3965 Hydrochloride

CAS: 405911-17-3

Rif. TR-G930985

Informazioni sul prodotto

• Nome: GW 3965 Hydrochloride
• Sinonimi: GW 3965A Hydrochloride, 2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic Acid Hydrochloride, 3-[3-[N-(2-Chloro-3-trifluoromethylbenzyl)(2,2-diphenylethyl)amino]propoxy]phenylacetic Acid Hydrochloride, 3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-benzeneacetic Acid Hydrochloride, 2-[3-[3-[[2-Chloro-3-(Trifluoromethyl)Phenyl]Methyl-(2,2-Diphenylethyl)Amino]Propoxy]Phenyl]Acetic Acid,Hydrochloride, GW3965 hydrochloride, [3-(3-{[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)phenyl]acetic acid hydrochloride (1:1), Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride (1:1)

Descrizione

Applications GW3965 Hydrochloride, is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXR. GW3965 has shown potent anti-inflammatory activity in both irritant and allergic contact models of dermatitis, requiring the participation of both LXRα and LXRβ.
References Fowler, A.J., et. al.: J. Invest. Dermatol., 120, 246 (2003)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 582.053646
• Formula: C₃₃H₃₁ClF₃NO₃•HCl
• Colore/Forma: Neat
• InChI: InChI=1S/C33H31ClF3NO3.ClH/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26;/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40);1H
• InChI key: InChIKey=NMPUWJFHNOUNQU-UHFFFAOYSA-N
• SMILES: Cl.O=C(O)Cc1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1