m-Hydroxycocaine-D3

CAS: 253775-19-8

Rif. TR-H825444

Informazioni sul prodotto

• Nome: m-Hydroxycocaine-D3
• Sinonimi: (1R,2R,3S,5S)-3-[(3-Hydroxybenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester-D3,[1R-(exo,exo)]-3-[(3-Hydroxybenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester-D3, 3'-Hydroxybenzoylecgonine Methyl Ester-D3, 3'-Hydroxycocaine-D3
• CAS: 253775-19-8

Descrizione

Applications m-Hydroxycocaine-D3 is a labelled analogue of m-Hydroxycocaine (H825440). m-Hydroxycocaine is a metabolite of Cocaine (HCl: C633500), a vasoconstrictive agent that is highly addictive and has high potential for abuse. The mechanism by which Cocaine induces dependence is unknown, but it is hypothesized that it works by blocking the dopamine transporter, increasing the amount of free dopamine in the brain.
References Carrera, M., et al.: Nature, 378, 727 (1995); Moore, T., et al.: Am. J. Obst. Gyne., 155, 883 (1986); Volkow, N., et al.: Nature, 386, 827 (1997)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 322.38
• Formula: C₁₇H₁₈D₃NO₅
• Colore/Forma: White to Off-White Solid
• InChI: InChI=1S/C17H21NO5/c1-18-11-6-7-13(18)15(17(21)22-2)14(9-11)23-16(20)10-4-3-5-12(19)8-10/h3-5,8,11,13-15,19H,6-7,9H2,1-2H3/t11-,13+,14-,15+/m0/s1/i1D3
• InChI key: InChIKey=IQXBUEUAOWARGT-ZRYGNULPSA-N
• SMILES: [2H]C([2H])([2H])N1[C@H]2CC[C@@H]1[C@@H](C(=O)OC)[C@@H](OC(=O)c1cccc(O)c1)C2