2-Hydroxy Atorvastatin Lactone

CAS: 163217-74-1

Rif. TR-H828955

Informazioni sul prodotto

• Nome: 2-Hydroxy Atorvastatin Lactone
• Sinonimi: 1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-, 1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-, (2R-trans)-, 5-(4-Fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide, (2R-trans)-5-(4-Fluorophenyl)-2-(1-methylethyl)-N-(2-hydroxyphenyl)-4-phenyl-1-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1H-pyrrole-3-carboxamide, 2-Hydroxyatorvastatin lactone, 2-Hydroxyatorvastatin δ-lactone, (4R,6R)-6-[2-[2-(4-Fluorophenyl)-4-(2-hydroxyphenylcarbamoyl)-5-(1-methylethyl)-3-phenyl-1H-pyrrol-1-yl]ethyl]-4-hydroxytetrahydro-2H-pyran-2-one
• Marchio: TRC
• Descrizione: Impurity Atorvastatin 2-Hydroxy LactoneStability HygroscopicApplications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

Proprietà chimiche

• Peso molecolare: 556.62
• Formula: C₃₃H₃₃FN₂O₅
• Colore/Forma: Off White Solid
• InChI: InChI=1S/C33H33FN2O5/c1-20(2)31-30(33(40)35-26-10-6-7-11-27(26)38)29(21-8-4-3-5-9-21)32(22-12-14-23(34)15-13-22)36(31)17-16-25-18-24(37)19-28(39)41-25/h3-15,20,24-25,37-38H,16-19H2,1-2H3,(H,35,40)/t24-,25-/m1/s1
• InChI key: InChIKey=MNECBMZJZFGTIK-JWQCQUIFSA-N
• SMILES: CC(C)c1c(C(=O)Nc2ccccc2O)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1