cis-1-Hydroxy-2,7-diamino Mitosene

CAS: 98462-75-0

Rif. TR-H939705

Informazioni sul prodotto

• Nome: cis-1-Hydroxy-2,7-diamino Mitosene
• Sinonimi: 1H-Pyrrolo[1,2-a]indole-5,8-dione, 2,7-diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-, (1S,2S)-, 1H-Pyrrolo[1,2-a]indole-5,8-dione, 2,7-diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-, (1S-cis)-, (1S,2S)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-pyrrolo[1,2-a]indole-5,8-dione, (1S-cis)-1-Hydroxy-2,7-diaminomitosene, (1S,2S)-1-Hydroxy-2,7-diaminomitosene, (1S)-cis-1-Hydroxy-2,7-diamino Mitosene
• Marchio: TRC
• Descrizione: Applications cis-1-Hydroxy-2,7-diamino Mitosene is derived from Mitomycin C (M371900), which is an antitumor antibiotic. It is antineoplastic. Also, it is an oxazolidinone derivative resulting from a cyclization reaction of bicarbonate with the aziridine ring of aziridinomitosene.References Kinoshita, S., et al.: J. Med. Chem., 14, 13 (1971); Beijnen, J.H., et al.: Anal. Profiles Drug Subs., 16, 361 (1986); Paz, M. M.: Bioorg. Med. Chem. Lett., 20, 31-34 (2010)

Proprietà chimiche

• Peso molecolare: 320.30
• Formula: C₁₄H₁₆N₄O₅
• Colore/Forma: Neat
• InChI: InChI=1S/C14H16N4O5/c1-4-8(16)13(21)7-5(3-23-14(17)22)9-12(20)6(15)2-18(9)10(7)11(4)19/h6,12,20H,2-3,15-16H2,1H3,(H2,17,22)/t6-,12-/m0/s1
• InChI key: InChIKey=XNHZZRIKMUCTHU-QTTZVWFDSA-N
• SMILES: CC1=C(N)C(=O)c2c(COC(N)=O)c3n(c2C1=O)C[C@H](N)[C@@H]3O