trans-4-Hydroxy-lomustine

CAS: 56239-24-8

Rif. TR-H942995

Informazioni sul prodotto

• Nome: trans-4-Hydroxy-lomustine
• Sinonimi: 1-(2-Chloroethyl)-3-(trans-4-hydroxycyclohexyl)-1-nitrosourea, N-(2-Chloroethyl)-N'-(trans-4-hydroxycyclohexyl)-N-nitrosourea, NSC 239717, trans-4-Hydroxy CCNU

Descrizione

Applications trans-4-Hydroxy-lomustine is an impurity of lomustine (L469440) which is a chloroethylnitrosourea derivative with antitumor activity. Lomustine is similar to carmustine, chlorozotocin, nimustine, and ranimustine.
References Johnston, T.P., et al.: J. Med. Chem., 9, 892 (1966); Oliverio, V.T., et al.: Cancer Res., 30, 1330 (1970); Thompson, G.R., et al.: Toxicol. Appl. Pharmacol., 21, 405 (1972); Al-Shammary, F.J., et al.: Anal. Profiles Drug Subs., 19, 315 (1990)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 249.69
• Formula: C₉H₁₆ClN₃O₃
• Colore/Forma: Neat
• InChI: InChI=1S/C9H16ClN3O3/c10-5-6-13(12-16)9(15)11-7-1-3-8(14)4-2-7/h7-8,14H,1-6H2,(H,11,15)/t7-,8-
• InChI key: InChIKey=BTNKSMIZKSHDNT-ZKCHVHJHSA-N
• SMILES: O=NN(CCCl)C(=O)N[C@H]1CC[C@H](O)CC1