3-Hydroxyphenazepam

CAS: 70030-11-4

Rif. TR-H949550

Informazioni sul prodotto

• Nome: 3-Hydroxyphenazepam
• Sinonimi: 7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one, 2H-1,4-benzodiazepin-2-one, 7-bromo-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-

Descrizione

Applications 3-Hydroxyphenazepam is a metabolite of Phenazepam (P295300), a benzodiazepine drug, which is used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. It can be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety.
References Ogiso, T., et al.: Chem. Pharm. Bull., 37, 446 (1989); Gu, Q., et al.: J. Med. Chem., 36, 1001 (1993); Bekhterev, V.N., et al.: Pharm. Chem. J., 42, 95 (2008)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 365.61
• Formula: C₁₅H₁₀BrClN₂O₂
• Colore/Forma: Neat
• InChI: InChI=1S/C15H10BrClN2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)
• InChI key: InChIKey=KRJKJUWAZOWXNV-UHFFFAOYSA-N
• SMILES: O=C1Nc2ccc(Br)cc2C(c2ccccc2Cl)=NC1O