Isavuconazole-d4

CAS: 1346598-58-0

Rif. TR-I777832

Informazioni sul prodotto

• Nome: Isavuconazole-d4
• Sinonimi: 4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile-d4, 2R,3R)-3-[4-(4-Cyanophenyl)thiazol-2-yl]-2-(2,5- difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol-d4, BAL 4815-d4, RO 0094815-d4

Descrizione

Applications Labelled Isavuconazole (I777832). It is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedosporium spp., Candida spp., the Zygomycetes and Cryptococcus spp.
References Ohwada, J., et al.: Bioorg. Med. Chem. Lett., 13, 191 (2003), Guinea, J., et al.: Antimicrob. Agents Chemother., 52, 1396 (2008)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 441.49
• Formula: C₂₂H₁₃D₄F₂N₅OS
• Colore/Forma: White To Yellow
• SMILES: [2H]c1c([2H])c(-c2csc([C@H](C)[C@](O)(Cn3cncn3)c3cc(F)ccc3F)n2)c([2H])c([2H])c1C#N