(2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione

CAS: 145986-07-8

Rif. TR-L172535

Informazioni sul prodotto

• Nome: (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione
• Sinonimi: 2,4(1H,3H)-Pyrimidinedione, 1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)- (9CI), 1,3-Oxathiolane, 2,4(1H,3H)-pyrimidinedione deriv., 1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidine-2,4(1H,3H)-dione, Lamivudine Imp. J (EP)
• Marchio: TRC
• Descrizione: Impurity Lamivudine EP Impurity JApplications (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione (Lamivudine EP Impurity J) is an impurity of Lamivudine (L172500). (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is also being further studied to determine its potential as an anti-HIV agent.References Jeong, L., et al.: J. Med. Chem., 36, 181 (1993)

Proprietà chimiche

• Peso molecolare: 230.24
• Formula: C₈H₁₀N₂O₄S
• Colore/Forma: White
• InChI: InChI=1S/C8H10N2O4S/c11-3-7-14-6(4-15-7)10-2-1-5(12)9-8(10)13/h1-2,6-7,11H,3-4H2,(H,9,12,13)/t6-,7+/m0/s1
• InChI key: InChIKey=BNVOMPQTQUUYHU-NKWVEPMBSA-N
• SMILES: O=c1ccn([C@@H]2CS[C@H](CO)O2)c(=O)[nH]1