N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-Pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride

CAS: 1260590-51-9

Rif. TR-M203523

Informazioni sul prodotto

• Nome: N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-Pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride
• Sinonimi: Tofacitinib N-Descyanoacetyl Hydrochloride Impurity
• Marchio: TRC

Descrizione

Applications N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-Pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride, is a substance used in the identification of related substances in the degradation products of tofacitinib citrate using LC-MS technique for process monitoring and quality assurance. A reagent for the synthesis of Tofacitinib (CP-690,550), a Janus tyrosine kinase (JAK3) specific inhibitor.
References Wu, X., et al.: J. Pharm. Biomed. Anal., 143, 17 (2017); Marican, A., et al.: Tetrahedron Lett., 54, 5096 (2013)

Proprietà chimiche

• Peso molecolare: 281.78
• Formula: C₁₃H₁₉N₅·HCl
• Colore/Forma: Neat
• InChI: InChI=1S/C13H19N5.ClH/c1-9-3-5-14-7-11(9)18(2)13-10-4-6-15-12(10)16-8-17-13;/h4,6,8-9,11,14H,3,5,7H2,1-2H3,(H,15,16,17);1H/t9-,11+;/m1./s1
• InChI key: InChIKey=CJRKOJYCZNKFRI-XQKZEKTMSA-N
• SMILES: C[C@@H]1CCNC[C@@H]1N(C)c1ncnc2[nH]ccc12.Cl