12-O-Methyl Clarithromycin (~90%)

CAS: 128940-83-0

Rif. TR-M294630

Informazioni sul prodotto

• Nome: 12-O-Methyl Clarithromycin (~90%)
• Sinonimi: 6,12-Di-O-methylerythromycin, Oxacyclotetradecane, erythromycin deriv., 12-O-Methylclarithromycin, 6,12-Di-O-methylerythromycin A, Clarithromycin Imp. F (EP)

Descrizione

Impurity Clarithromycin EP Impurity F
Applications 12-O-Methyl Clarithromycin (Clarithromycin EP Impurity F) is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells.
References Chen, X. et al.: Zhong. Yao., 17, 32 (2008); Yoshida, H. et al.: Jap. J. Antibiot., 53, 615 (2000); Omura, S. et al.: Yakug. Zas., 112, 593 (1992);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 761.98
• Formula: C₃₉H₇₁NO₁₃
• Purezza: >90%
• Colore/Forma: Neat
• InChI: InChI=1S/C39H71NO13/c1-16-27-39(10,48-15)32(43)22(4)29(41)20(2)18-38(9,47-14)34(53-36-30(42)26(40(11)12)17-21(3)49-36)23(5)31(24(6)35(45)51-27)52-28-19-37(8,46-13)33(44)25(7)50-28/h20-28,30-34,36,42-44H,16-19H2,1-15H3/t20-,21-,22+,23+,24-,25+,26+,27-,28+,30-,31+,32-,33+,34-,36+,37-,38-,39-/m1/s1
• InChI key: InChIKey=ZABLXHVYLJLDOX-HIKKGGSBSA-N
• SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)OC