Metanicotine-d3

CAS: 220088-40-4

Rif. TR-M321252

Informazioni sul prodotto

• Nome: Metanicotine-d3
• Sinonimi: 3-Buten-1-amine, N-(methyl-d3)-4-(3-pyridinyl)-, (3E)- (9CI), Methyl-d3 Metanicotine, (E)-Metanicotine-D3 (methyl-D3), Rivanicline-D3 (N-methyl-D3), (3E)-N-(Methyl-d3)-4-(3-pyridinyl)-3-buten-1-amine, trans-Metanicotine-d3
• Marchio: TRC
• Descrizione: Applications Metanicotine-d3 is the isotope labelled analog of Metanicotine (M321250); an alkaloid found in the leaves of Duboisia Hopwoodii and a constitutent of tobacco smoke. Also used as a potential drug for the treatment of senile dementia of the Alzheimer’s type, and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to peripheral ganglionic and muscle-type nicotinic acetylcholine receptors. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Schmeltz, I., et al.: J. Sci. Food Agric., 15, 744 (1964); Griffin, W.J. and Luanratana, O.: Phytochemistry, 21, 499 (1982); Jacob III, P., et al.: J. Chromatogr., 619, 49 (1993); Lippiello, P.M., et al.: J. Pharm. Exp. Therap., 279, 1422 (1996)

Proprietà chimiche

• Peso molecolare: 165.25
• Formula: C₁₀₂H₃H₁₁N₂
• Colore/Forma: Neat
• InChI: InChI=1S/C10H14N2/c1-11-7-3-2-5-10-6-4-8-12-9-10/h2,4-6,8-9,11H,3,7H2,1H3/b5-2+/i1D3
• InChI key: InChIKey=JUOSGGQXEBBCJB-PAMUQJMYSA-N
• SMILES: [2H]C([2H])([2H])NCC/C=C/c1cccnc1