4-​(4-Morpholinyl)​-1,​2,​5-​thiadiazol-​3(2H)​-​one 1-Oxide

CAS: 75202-36-7

Rif. TR-M725175

Informazioni sul prodotto

• Nome: 4-​(4-Morpholinyl)​-1,​2,​5-​thiadiazol-​3(2H)​-​one 1-Oxide
• Sinonimi: Timolol Maleate Imp. G (EP), Timolol Imp. G (EP), 3-Hydroxy-4-morpholino-1,2,5-thiadiazole 1-Oxide, 4-(4-Morpholinyl)-1,2,5-thiadiazol-3(2H)-one 1-oxide, 4-(Morpholin-4-yl)-1,2,5-thiadiazol-3(2H)-one 1-oxide, Timolol Maleate Impurity G, Timolol Impurity G

Descrizione

Impurity Timolol EP Impurity G; Timolol BP Impurity G
Stability Moisture Sensitive
Applications 4-​(4-Morpholinyl)​-1,​2,​5-​thiadiazol-​3(2H)​-​one 1-Oxide (Timolol EP Impurity G; Timolol BP Impurity G) is an impurity of Timolol (T4437005), an antihypertensive, an adrenergic blocking agent (1); antiarrhythmic (class II); antianginal; antiglaucoma (2) and antihypertensive (3) agent.
References 1. Wasson, B. et al.: J. Med. Chem. 1972 Jun;15(6):651-5.2. Heel, R. et al.: Drugs. 1979 Jan;17(1):38-55.3. Rofman, et al.: Hypertension. 1980 Sep-Oct;2(5):643-8.

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 203.22
• Formula: C₆H₉N₃O₃S
• Colore/Forma: White
• InChI: InChI=1S/C6H9N3O3S/c10-6-5(7-13(11)8-6)9-1-3-12-4-2-9/h1-4H2,(H,8,10)
• InChI key: InChIKey=AAYSTAZTUCBWCK-UHFFFAOYSA-N
• SMILES: O=C1NS(=O)N=C1N1CCOCC1