Nalmefene-d3

CAS: 55096-26-9

Rif. TR-N284402

Informazioni sul prodotto

• Nome: Nalmefene-d3
• Sinonimi: (5α)-17-(Cyclopropylmethyl-d3)-4,5-epoxy-6-methylenemorphinan-3,14-diol, 6-Deoxo-6-methylenenaltrexone-d3, 6-Desoxy-6-methylenenaltrexone-d3, JF 1-d3, Nalmetrene-d3, ORF 11676-d3
• Marchio: TRC

Descrizione

Applications A structural labelled analog of Naltrexone (N285780) with opiate antagonist activity used in pharmaceutical treatment of alcoholism. Other pharmacological applications of this compound aim to reduce food cravings, drug abuse and pulmonary disease in affected individuals. Used as an opioid-induced tranquilizer on large animals in the veterinary industry. Narcotic antagonist.
References Brittain, H.G., et al.: Anal. Profiles Drug Subs. Excip., 24, 351 (1996), Anton, R., et al.: J. Clin. Psychopharmacol., 24, 421 (2004), Bart, G., et al.: Neuropsychopharmacol., 30, 2254 (2005), Wu, X., et al.: Chem. Pharmacol. Bull., 54, 977 (2006),

Proprietà chimiche

• Peso molecolare: 342.45
• Formula: C₂₁H₂₂D₃NO₃
• Colore/Forma: Neat
• InChI: InChI=1S/C21H25NO3/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13/h4-5,13,16,19,23-24H,1-3,6-11H2/t16-,19+,20+,21-/m1/s1/i11D2,13D
• InChI key: InChIKey=WJBLNOPPDWQMCH-TVFUAGGXSA-N
• SMILES: [2H]C1(C([2H])([2H])N2CC[C@]34c5c6ccc(O)c5O[C@H]3C(=C)CC[C@@]4(O)[C@H]2C6)CC1