4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
CAS: 641569-94-0
Rif. TR-N465305
1g | 182,00 € | ||
250mg | 99,00 € | ||
2500mg | 266,00 € |
Informazioni sul prodotto
- Benzoic acid
- 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-
- Nilotinib Hydrochloride Monohydrate Impurity D
- Nilotinib Impurity D
- 4-Methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzoic acid
- Benzoic acid, 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-
- 4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzoic acid
- 4-Methyl-3-[(4-(3-Pyridinyl)-Pyrimidinyl)Amino]Benzoic Acid
- 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidiny]amino]benzoicacid
Stability Hygroscopic
Applications 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is used in the preparation of (pyridinyl)-N-[(triazolyl)phenyl]pyrimidinamine derivatives and (pyridinyl)-N-[oxadiazolyl)phenyl]pyrimidinamine derivatives, and can be used in the detection of their activity as antileukemia agents (neoplastic stem cell leukemia). 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is also a Nilotinib (N465300) intermediate, which might be useful in treatment of chronic myelogenous leukemia.
References Li, Y., et al.: Bioorg. Med. Chem. Lett., 26, 1419-1427 (2016)
Proprietà chimiche
Richiesta tecnica su: TR-N465305 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
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