TR-N900550 - nsc-697923 | 343351-67-7

NSC697923

<p>NSC697923 is a small molecule that inhibits the activity of ubiquitin ligases. It has shown to have anti-inflammatory properties in diabetic patients and radiation-induced skin damage. NSC697923 also has potential applications in autoimmune diseases and as a cancer therapy, with the ability to inhibit autophagy.</p>

<p>NSC-697923 inhibits UBE2N, triggers p53-dependent and JNK-mediated apoptosis, blocks DNA damage and NF-κB signaling in neuroblastoma cells.</p>