3-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic Acid Methyl Ester

CAS: 103335-41-7

Rif. TR-O847260

Informazioni sul prodotto

• Nome: 3-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic Acid Methyl Ester
• Sinonimi: Methyl 3-Oxo-4-aza-5alpha-androst-1-ene-17beta-carboxylate, Finasteride Imp. B (EP), Delta-1-Aza Ester of Finasteride, 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, methyl ester, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-, 4-Azaandrost-1-ene-17-carboxylic acid, 3-oxo-, methyl ester, (5alpha,17beta)-, 17beta-(Methoxycarbonyl)-4-aza-5alpha-androst-1-en-3-one, 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, methyl ester, [4aR-(4aalpha,4bbeta,6aalpha,7alpha,9abeta,9balpha,11abeta)]-, 3-Oxo-4-aza-5alpha-androst-1-en-17beta-carboxylic acid methyl ester, Methyl 3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxylate, Finasteride Impurity B, 17β-(Methoxycarbonyl)-4-aza-5α-androst-1-en-3-one, 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, methyl ester, [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)]-, 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, methyl ester, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-, 3-Oxo-4-aza-5α-androst-1-en-17β-carboxylic acid methyl ester, 4-Azaandrost-1-ene-17-carboxylic acid, 3-oxo-, methyl ester, (5α,17β)-, Methyl 3-Oxo-4-Aza-5-Alpha-Androst-1-Ene-17-Beta-Carboxylate, Methyl 3-oxo-4-aza-5α-androst-1-ene-17β-carboxylate, methyl (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate

Descrizione

Impurity Finasteride EP Impurity B
Applications 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester (Finasteride EP Impurity B) is an impurity of Finasteride (F342000) and Dutasteride (D735000). An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. Finasteride impurity.
References Bakshi., et al.: J. Med. Chem., 38, 3189 (1995),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 331.45
• Formula: C₂₀H₂₉NO₃
• Colore/Forma: White
• InChI: InChI=1S/C20H29NO3/c1-19-10-8-14-12(13(19)5-6-15(19)18(23)24-3)4-7-16-20(14,2)11-9-17(22)21-16/h9,11-16H,4-8,10H2,1-3H3,(H,21,22)/t12-,13-,14-,15+,16+,19-,20+/m0/s1
• InChI key: InChIKey=WMSQGMYJYBSBKA-JIZLFPMWSA-N
• SMILES: COC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)C3CC[C@]12C