Pteroic Acid (>85%)

CAS: 119-24-4

Rif. TR-P840110

Informazioni sul prodotto

• Nome: Pteroic Acid (>85%)
• Sinonimi: 4-[[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]benzoic Acid, Folic Acid Imp. D (EP), Pteroic Acid, Folic Acid Hydrate Impurity D, Folic Acid Impurity D, 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, 4-{[(2-Amino-4-Oxo-1,4-Dihydropteridin-6-Yl)Methyl]Amino}Benzoic Acid, Benzoic acid, 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-, Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-, Benzoic acid, p-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-, NSC 14972, P-((2-Amino-4-Hydroxypteridin-6-Yl)Methylamino)Benzoic Acid, Pyrofolic acid, p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic acid

Descrizione

Impurity Methotrexate EP Impurity D N-Desmethyl Impurity
Applications Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase.
References Vickers, P.J. et al.: Can. J. Biochem. Cell Biol., 63, 777 (1985): Tafolla, W.H. et al.: J. Pharmac. Sci., 70, 1273 (1981); Iwai, K. et al.: J. Butrit. Sci. Vitaminol., 23, 95 (1977);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 312.28
• Formula: C₁₄H₁₂N₆O₃
• Purezza: >85%
• Colore/Forma: Neat
• InChI: InChI=1S/C14H12N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,6,16H,5H2,(H,22,23)(H3,15,17,19,20,21)
• InChI key: InChIKey=JOAQINSXLLMRCV-UHFFFAOYSA-N
• SMILES: N=c1[nH]c(=O)c2nc(CNc3ccc(C(=O)O)cc3)cnc2[nH]1