Succinylacetone-13C7

CAS: 51568-18-4

Rif. TR-S692063

Informazioni sul prodotto

• Nome: Succinylacetone-13C7
• Sinonimi: 4,6-dioxoheptanoic acid, Ccris 1387, Heptanoic acid, 4,6-dioxo-, Nsc 174804, Succinyl acetone, Succinylacetone

Descrizione

Applications Succinylacetone-13C7 is a labelled analogue of Succinylacetone (S692060). Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.
References Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991), Lindstedt, S., et al.: Lancet, 340, 813 (1992), Schulze, A., et al.: Clin. Chem., 47, 1424 (2001), Allard, P., et al.: Clin. Biochem., 37, 1010 (2004),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 158.15
• Formula: C₇H₁₀O₄
• Colore/Forma: Neat
• InChI: InChI=1S/C7H10O4/c1-5(8)4-6(9)2-3-7(10)11/h2-4H2,1H3,(H,10,11)
• InChI key: InChIKey=WYEPBHZLDUPIOD-BNUYUSEDSA-N
• SMILES: [13CH3][13C](=O)[13CH2][13C](=O)[13CH2][13CH2][13C](=O)O