Sulindac Sulfone-d6

CAS: 59973-80-7

Rif. TR-S699227

Informazioni sul prodotto

• Nome: Sulindac Sulfone-d6
• Sinonimi: (Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic Acid-d6, Aptosyn-d6, Exisulind-d6, FGN 1-d6, Prevatec-d6, (1Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic acid, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-, (1Z)-, 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-, (Z)-, Aposulind, Aptosyn, Exisulind, Fgn-1, Prevatac(former Brand Name), Prevatec, Sulindac sulfone, cis-5-Fluoro-2-methyl-1-[p-methylsulfonylbenzylidenyl]indene-3-acetic acid

Descrizione

Applications Labelled analogue of Sulindac Sulfone, an active metabolite of Sulindac. Inducer of apoptosis independent of cyclooxygenase inhibition. Inhibits cell growth by inducing apoptosis.
References Piazza, G.A. et al.: Cancer Res., 55, 3310 (1995);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 378.45
• Formula: C₂₀H₁₁D₆FO₄S
• Colore/Forma: Neat
• InChI: InChI=1S/C20H17FO4S/c1-12-17(9-13-3-6-15(7-4-13)26(2,24)25)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-/i2D3,9D,11D2
• InChI key: InChIKey=MVGSNCBCUWPVDA-NUJVTHJYSA-N
• SMILES: [2H]/C(=C1\C(C)=C(C([2H])([2H])C(=O)O)c2cc(F)ccc21)c1ccc(S(=O)(=O)C([2H])([2H])[2H])cc1