Thyroxine Sodium Salt

CAS: 55-03-8

Rif. TR-T425601

Informazioni sul prodotto

• Nome: Thyroxine Sodium Salt
• Sinonimi: L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1), L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt (9CI), Thyroxine, monosodium salt, L- (8CI), Berlthyrox, Dathroid, Droxine, Eferox, Elthyrone, Elthyroxine, Eltroxin, Euthyrox, Eutirox, L-Thyroxin Henning, L-Thyroxine monosodium salt, L-Thyroxine sodium, L-Thyroxine sodium salt, Laevoxin, Letrox, Letter, Levaxin, Leventa, Levo-T, Levolet, Levoroxine, Levothroid, Levothyrox, Levothyroxine sodium, Levotirox, Levotiroxina, Levoxyl, Monosodium thyroxine, NSC 259940, Novothyrox, Oroxine, Puran T 4, Sodium L-thyroxine, Sodium levothyroxine, Sodium thyroxin, Sodium thyroxinate, Sodium thyroxine, Synthroid, Synthroid sodium, Synthrox, T 4KP, T4 Montpellier 100, Thevier, Throxinique, Thyradin, Thyradin S, Thyrax Duotab, Thyrex, Thyro 4, Thyrosit, Thyroxevan, Thyroxine sodium, Tiroidine, Tirosint, Unithroid
• Marchio: TRC

Descrizione

Stability Hygroscopic
Applications One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),

Proprietà chimiche

• Peso molecolare: 798.85
• Formula: C₁₅H₁₀I₄NO₄·Na
• Colore/Forma: Neat
• InChI: InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/m0./s1
• SMILES: N[C@@H](Cc1cc(I)c(Oc2cc(I)c([O-])c(I)c2)c(I)c1)C(=O)O.[Na+]