4-(4-(4-(4H-1,2,4-Triazol-4-yl)phenyl)piperazin-1-yl)phenyl Acetate

Rif. TR-T767468

Informazioni sul prodotto

• Nome: 4-(4-(4-(4H-1,2,4-Triazol-4-yl)phenyl)piperazin-1-yl)phenyl Acetate
• Sinonimi: [4-[4-[4-(1,2,4-triazol-4-yl)phenyl]piperazin-1-yl]phenyl] acetate
• Marchio: TRC
• Descrizione: Applications 4-(4-(4-(4H-1,2,4-Triazol-4-yl)phenyl)piperazin-1-yl)phenyl Acetate is an intermediate in the synthesis of Deoxo Anhydro Itraconazole Bromide (D231675). Deoxo Anhydro Itraconazole Bromide is an impurity of Itraconazole (I937500), which is orally active antimycotic drug structurally related to Ketoconazole (K186000). Antifungal.References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)

Proprietà chimiche

• Peso molecolare: 363.413
• Formula: C₂₀H₂₁N₅O₂
• Colore/Forma: Neat
• InChI: InChI=1S/C20H21N5O2/c1-16(26)27-20-8-6-18(7-9-20)24-12-10-23(11-13-24)17-2-4-19(5-3-17)25-14-21-22-15-25/h2-9,14-15H,10-13H2,1H3
• InChI key: InChIKey=LILUVKXYXBODFN-UHFFFAOYSA-N
• SMILES: CC(=O)Oc1ccc(N2CCN(c3ccc(-n4cnnc4)cc3)CC2)cc1