4-(Trifluoromethoxy)aniline

CAS: 461-82-5

Rif. TR-T790700

Informazioni sul prodotto

• Nome: 4-(Trifluoromethoxy)aniline
• Sinonimi: 4-(Trifluoromethoxy)-benzenamine, (4-(Trifluoromethoxy)phenyl)amine, 1-Amino-4-(trifluoromethoxy)benzene, 4-(Trifluoromethoxy)benzenamine, 4-Trifluoromethoxybenzeneamine, 4-[(Trifluoromethyl)oxy]aniline, p-(Trifluoromethoxy)aniline, p-Trifluoromethoxyphenylamine, p-Anisidine, α,α,α-trifluoro- (6CI,7CI,8CI), α,α,α-Trifluoro-p-anisidine
• Marchio: TRC
• Descrizione: Stability HygroscopicApplications 4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole (R510000), a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Cilibrizzi, A., et al.: J. Med. Chem., 52, 5044 (2009), Verhaeghe, P., et al.: Bioorg. Med. Chem., 17, 4313 (2009), Chandregowda, V., et al.: Eur. J. Med. Chem., 44, 3046 (2009), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994); Piras, S. et al.: Eur. j. Med. Chem., 75, 169 (2014); Vyas, V. et al.: Eur. J. Med. Chem., 82, 385 (2014)

Proprietà chimiche

• Peso molecolare: 177.12
• Formula: C₇H₆F₃NO
• Colore/Forma: Neat
• InChI: InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2
• InChI key: InChIKey=XUJFOSLZQITUOI-UHFFFAOYSA-N
• SMILES: Nc1ccc(OC(F)(F)F)cc1