3alpha,6alpha,7alpha-Trihydroxy-5beta-cholanic Acid

CAS: 547-75-1

Rif. TR-T795105

Informazioni sul prodotto

• Nome: 3alpha,6alpha,7alpha-Trihydroxy-5beta-cholanic Acid
• Sinonimi: Cholan-24-oic acid, 3,6,7-trihydroxy-, (3a,5ß,6a,7a)-, 5ß-Cholan-24-oic acid, 3a,6a,7a-trihydroxy- (8CI), 5ß-Cholanic acid, 3a,6a,7a-trihydroxy- (7CI), (3a,5ß,6a,7a)-3,6,7-Trihydroxycholan-24-oic acid, 3a,6a,7a-Trihydroxy-5ß-cholan-24-oic acid, 3a,6a,7a-T, (3α,5β,6α,7α)-3,6,7-Trihydroxycholan-24-oic acid, 3,6,12-Trihydroxycholan-24-oic acid, 3alpha,6alpha,7alpha-Trihydroxy-5beta-cholan-24-oic acid, 3α,6α,7α-Trihydroxy-5β-cholanic acid, 3α,6α,7α-Trihydroxy-5β-cholanoic acid, 5β-Cholan-24-oic acid, 3α,6α,7α-trihydroxy-, 5β-Cholanic acid, 3α,6α,7α-trihydroxy-, 5β-Cholanic acid-3α,6α,7α-triol, 6α-Hydroxychenodeoxycholic acid, Cholan-24-oic acid, 3,6,7-trihydroxy-, (3alpha,5beta,6alpha,7alpha)-, Cholan-24-oic acid, 3,6,7-trihydroxy-, (3α,5β,6α,7α)-, Hyocholic acid, Iocholic acid, α-Hyocholic acid, γ-Muricholic acid

Descrizione

Applications 3α,6α,7α-Trihydroxy-5β-cholanic Acid is one of the bile acids categorizes under muricholic acid, a group of bile acids found in human urine due to its additional hydroxyl groups. The synthesis of 3α,6α,7α-Trihydroxy-5β-cholanic Acid was shown to be promoted due to overexpression of cholesterol 7α-hydroxylase enzyme.
References Debray, D., et al.: Gastroenterol., 142, 1581 (2012); Li, T.G., et al.: Hepatol., 53, 996 (2011);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 408.571
• Formula: C₂₄H₄₀O₅
• Colore/Forma: Neat
• InChI: InChI=1S/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13-,14-,15-,16+,17+,18+,20+,21-,22+,23-,24-/m1/s1