(3α,5β,7α,12α)-3,7,12-Tris(ethoxymethoxy)-cholest-24-en-26-oic Acid Ethyl Ester

Rif. TR-T887905

Informazioni sul prodotto

• Nome: (3α,5β,7α,12α)-3,7,12-Tris(ethoxymethoxy)-cholest-24-en-26-oic Acid Ethyl Ester

Descrizione

Applications (3α,5β,7α,12α)-3,7,12-Tris(ethoxymethoxy)-cholest-24-en-26-oic Acid Ethyl Ester is an intermediate in the synthesis of (25R)-3β,7α,12α-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood.
References Schroepfer, G., et al.: Physiol. Rev., 80, 361 (2000); Bjorkhem, I.: J. Clin. Invest., 6, 725(2002); Bjorkhem, I., et al.: Arterio. hromb. Vascul. Biol., 22, 734 (2002)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 650.48
• Formula: C₃₈H₆₆O₈
• Colore/Forma: Neat
• InChI: InChI=1S/C38H66O8/c1-9-40-23-44-29-18-19-37(7)28(20-29)21-33(45-24-41-10-2)35-31-17-16-30(26(5)14-13-15-27(6)36(39)43-12-4)38(31,8)34(22-32(35)37)46-25-42-11-3/h15,26,28-35H,9-14,16-25H2,1-8H3/b27-15+/t26-,28+,29-,30-,31?,32?,33-,34+,35?,37+,38-/m1/s1
• InChI key: InChIKey=FLZZUWRPLFFVSA-IXYFMBKASA-N
• SMILES: CCOCO[C@H]1CC2C(C3CC[C@H]([C@H](C)CC/C=C(\C)C(=O)OCC)[C@]31C)[C@H](OCOCC)C[C@@H]1C[C@H](OCOCC)CC[C@]21C