Vadimezan

CAS: 117570-53-3

Rif. TR-V084950

Informazioni sul prodotto

• Nome: Vadimezan
• Sinonimi: 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic Acid, 5,6-Dimethyl-9-oxo-9H-xanthen-4-ylacetic Acid, 5,6-Dimethylxanthenone-4-acetic Acid, AS 1404, ASA 404, DMXAA, NSC 640488, 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic Acid, (5,6-Dimethyl-9-Oxo-Xanthen)-4-Acetic Acid, (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, 2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid, 5,6-Dimethyl-9-oxo-9H-xanthen-4-ylacetic acid, 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid, 5,6-Dimethylxanthenone-4-acetic acid, 5,6-Dimethylxanthenoneacetic Acid, 9H-Xanthene-4-acetic acid, 5,6-dimethyl-9-oxo-, As 1404, Asa 404, D5817, Dmxaa

Descrizione

Applications Vadimezan is a drug that displayed vascular-disrupting activity and induced haemorrhagic necrosis and tumour regression in pre-clinical animal models. It is a substrate for the immune adaptor protein STING in mice.
References Buchanan, C.M., et al.: Clin. Sci., 122, 449 (2012); Fruh, M., et la.: Clin. Lung. Cancer., 14, 34 (2013); Chem. and Eng. News page 24 Feb. 26, 2018

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 282.29
• Formula: C₁₇H₁₄O₄
• Colore/Forma: Neat
• InChI: InChI=1S/C17H14O4/c1-9-6-7-13-15(20)12-5-3-4-11(8-14(18)19)17(12)21-16(13)10(9)2/h3-7H,8H2,1-2H3,(H,18,19)
• InChI key: InChIKey=XGOYIMQSIKSOBS-UHFFFAOYSA-N
• SMILES: Cc1ccc2c(=O)c3cccc(CC(=O)O)c3oc2c1C