Informazioni sul prodotto
- 5ß-Ergosta-2,24-dien-26-oic acid
- 5,6ß-epoxy-4ß,22,27-trihydroxy-1-oxo-
- d-lactone
- (20S,22R)- (8CI)
- Withaferin A (7CI)
- 5,6-Epoxy-5H-cyclopenta[a]phenanthrene
- ergosta-2,24-dien-26-oic acid deriv.
- NSC 101088
- NSC 273757
- Withaferine
- Vedi altri sinonimi
- Withaferine A
- (4ß,5ß,6ß,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid d-lactone
- (4b,5b,6b,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic Acid d-Lactone
- 4b,27-Dihydroxy-1-oxo-5b,6b-epoxywitha-2,24-dienolide
- 5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic Acid d-Lactone
- 5,6-Epoxy-5H-cyclopenta[a]phenanthrene, ergosta-2,24-dien-26-oic acid deriv.
- 5β-Ergosta-2,24-dien-26-oic acid, 5,6β-epoxy-4β,22,27-trihydroxy-1-oxo-, δ-lactone, (20S,22R)-
- Ergosta-2,24-dien-26-oic acid, 5,6-epoxy-4,22,27-trihydroxy-1-oxo-, δ-lactone, (4β,5β,6β,22R)-
Applications Withaferin A is a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera. Withaferin A showed potent cytotoxicity against human head and neck squamous cell carcinoma (JMAR and MDA-1986). Withaferin A has recently been found to be a leptin sensitizer that can reduce the weight in obese mice fed in a high-fat diet (see C249500).
References Shohat, B., et al.: Cancer Chemother. Rep., 51, 271 (1967), Shohat, B., et al.: Int. J. Cancer., 8, 487 (1971); Chem. and Eng. News p. 6, Aug. 8, 2016
Proprietà chimiche
Richiesta tecnica su: TR-W499200 Withaferin A
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