CymitQuimica ha oltre 25 partner, tra i quali spicca il fornitore TargetMol
We have reached an agreement with TargetMol: CymitQuimica clients will benefit for a 20% discount on all TargetMol products until the end of the year.On our website you can find the products offered by this partner, which has become one of the world's most recognised compound libraries and small molecule inhibitors supplier. TargetMol offers approximately 120 compound libraries and a wide range of chemical products and kits for life sciences.
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Navitoclax
CAS:<p>View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2.Cited in 4 publications.</p>Formula:C47H55ClF3N5O6S3Purezza:95.82% - >99.99%Colore e forma:Pale Yellow SolidPeso molecolare:974.61Diacetolol
CAS:<p>Diacetolol is the major metabolite of acebutolol, a selective beta blockers used to treat hypertension, angina pectoris and arrhythmia.</p>Formula:C16H24N2O4Colore e forma:SolidPeso molecolare:308.37E3 Ligase Ligand-linker Conjugate 110
<p>E3LigaseLigand-linker Conjugate 110 is an E3 ligase and linker conjugate designed for the synthesis of BcI-2/BcI-xPROTAC degraders.</p>Formula:C30H40N4O8SPeso molecolare:616.25669Thalidomide-N-C3-O-C4-O-C3-OH
<p>Thalidomide-N-C3-O-C4-O-C3-OH is a conjugate of an E3 ligase ligand and a linker, used in the synthesis of the Aster-APROTAC degrader.</p>Formula:C23H31N3O7Peso molecolare:461.2162(S,R,S)-AHPC-CO-C9-NH2
CAS:(S,R,S)-AHPC-CO-C9-NH2 is a Von Hippel-Lindau (VHL) amino building block utilized in the synthesis of E3 ligase ligands required for PROTACs development.Formula:C32H49N5O4SPeso molecolare:599.83HER2-IN-20
<p>HER2-IN-20 (compound 32) is a potent and selective inhibitor of HER2WT and HER2YVMA, with IC50 values of 49 and 42 nM, respectively. It holds potential for research in non-small cell lung cancer (NSCLC).</p>Formula:C30H27ClFN7O2Peso molecolare:571.18988Diflufenican
CAS:Diflufenican (M&B 38544) increases the production of phytoene in carrot cell cultures by inducing the inhibition of phytoene desaturase gene expression.Formula:C19H11F5N2O2Purezza:99.62%Colore e forma:Odorlessness White SolidPeso molecolare:394.297-Bromoheptanoyl chloride
CAS:7-Bromoheptanoyl chloride is the link (ligand) in the formation of PROTACEGFR degrader 9.Formula:C7H12BrClOPeso molecolare:227.53Protein kinase inhibitor 7
CAS:Protein kinase inhibitor 7 functions as an inhibitor of protein kinase A (PKA) and protein kinase C (PKC). It impacts the autocrine motility factor (AMF) signaling pathway without affecting cell motility.Formula:C12H15N3O2SPeso molecolare:265.33Clomipramine
CAS:<p>Clomipramine treats OCD, depression, chronic pain, and may lower suicide risk in seniors; works by hindering serotonin reuptake.</p>Formula:C19H23ClN2Purezza:99.31% - 99.71%Colore e forma:SolidPeso molecolare:314.85(S,R,S)-Me-AHPC-amide-C3-alkyne
CAS:<p>(S,R,S)-Me-AHPC-amide-C3-alkyne is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), utilized in the synthesis of JWZ-5-13.</p>Formula:C29H38N4O4SPeso molecolare:538.70ORM-5029
ORM-5029 is the first antibody-drug conjugate (ADC) targeting the human epidermal growth factor receptor 2 (HER2), combining the highly potent GSPT1 degrader SMol006 with Pertuzumab. It is applicable in cancer research.Thonzylamine hydrochloride
CAS:Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.Formula:C16H23ClN4OPurezza:99.67%Colore e forma:White Crystalline PowderPeso molecolare:322.83SAE-IN-2
SAE-IN-2 (compound 6) is a potent inhibitor of sumoylation-activating enzyme (SAE) with an IC50 value of 27.8 nM.Formula:C27H30ClN5O5S2Peso molecolare:603.13769MUS81-IN-1
<p>MUS81-IN-1 (compound 23) is an MUS81 inhibitor, utilized in cancer research.</p>Formula:C23H21N3O5Peso molecolare:419.14812Platelet aggregation-IN-1
<p>Platelet aggregation-IN-1 (Compound 10e) acts as an inhibitor of platelet aggregation and can achieve complete (100%) inhibition of thrombin-induced platelet aggregation at a concentration of 50 μM.</p>Formula:C18H13N3O4Peso molecolare:335.09061Antibacterial agent 226
Antibacterialagent 226 (Compound 7f) is an antibacterial agent effective against Staphylococcus aureus strains, including methicillin-resistant S. aureus, with a MIC of 2 μg/mL. It exhibits cytotoxicity towards HEK293 cells with an IC50 of 1.9 μM.Formula:C24H26F3N3O2Peso molecolare:445.19771α-Amylase-IN-7
CAS:<p>α-Amylase-IN-7 (Compound 6e) is an inhibitor of α-Amylase, with an IC50 of 40 μM, indicating its potency. This compound shows potential as an anti-diabetic medication.</p>Formula:C18H15ClN6O2SPeso molecolare:414.87Cyproterone
CAS:<p>Cyproterone, an anti-androgen, treats female hirsutism and acne, and is used palliatively in prostate cancer.</p>Formula:C22H27ClO3Colore e forma:SolidPeso molecolare:374.9PROTAC PD-L1 degrader-1
PROTACPD-L1 degrader-1 is a CRBN-based PD-L1-PROTAC degrader with significant PD-L1 protein degradation capacity. It demonstrates strong PD-L1 degradation activity in 4T1 cells, with a DC50 of 0.609 μM. This compound is applicable to breast cancer research.
