CymitQuimica ha oltre 25 partner, tra i quali spicca il fornitore TargetMol
We have reached an agreement with TargetMol: CymitQuimica clients will benefit for a 20% discount on all TargetMol products until the end of the year.On our website you can find the products offered by this partner, which has become one of the world's most recognised compound libraries and small molecule inhibitors supplier. TargetMol offers approximately 120 compound libraries and a wide range of chemical products and kits for life sciences.
Finisce il 31 dic( 7 giorni restanti )
hCAIX-IN-16
CAS:hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.Formula:C20H20N8O2SPurezza:98%Colore e forma:SolidPeso molecolare:436.49hCAIX-IN-15
CAS:hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancerFormula:C18H14FN7O2SPurezza:98%Colore e forma:SolidPeso molecolare:411.41LIXIVAPTAN
CAS:Lixivaptan (VPA-985) is an orally active and selective vasopressin receptor V2 antagonist(Ki = 2.3 nM)Formula:C27H21ClFN3O2Purezza:98.36%Colore e forma:SolidPeso molecolare:473.93hCAIX-IN-14
CAS:hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM .Formula:C11H17ClN6O2SColore e forma:SolidPeso molecolare:332.81HDAC6-IN-14
HDAC6-IN-14, an inhibitor of HDAC6 (HDAC), exhibits high selectivity with an IC50 value of 42 nM, demonstrating over 100-fold selectivity compared to HDAC1,Formula:C24H30FN3O4Colore e forma:SolidPeso molecolare:443.51MtInhA-IN-1
MtInhA-IN-1: an oral selective MtInhA inhibitor, IC50 0.23 μM, effective against M. tuberculosis with MIC 0.4 μM.Formula:C21H22BrN3Colore e forma:SolidPeso molecolare:396.32TRK II-IN-1
CAS:<p>TRK II-IN-1: potent type II TRK inhibitor; IC50s: TRKA (3.3 nM), TRKB (6.4 nM), TRKC (4.3 nM), TRKA G667C (9.4 nM); also targets FLT3, RET, VEGFR2.</p>Formula:C29H31F3N8OPurezza:98%Colore e forma:SolidPeso molecolare:564.6NLRP3-IN-12
NLRP3-IN-12 inhibits NLRP3 inflammasome, curbing IL-1β release with 0.45 μM IC50, for inflammatory bowel disease research.Formula:C27H32ClNO7Colore e forma:SolidPeso molecolare:518STAT3-IN-15
STAT3-IN-15: Potent, oral STAT3 inhibitor for IPF, blocks STAT3 phosphorylation, cell migration, and EMT.Formula:C20H17F3N2O3SColore e forma:SolidPeso molecolare:422.42hCA IX-IN-2
hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferativeFormula:C23H24N2O4STeColore e forma:SolidPeso molecolare:552.11HSP90-IN-18
HSP90-IN-18 inhibits Hsp90 with 0.39 μM IC50, useful for viral, neurodegenerative, and inflammatory research.Formula:C25H33FO3Colore e forma:SolidPeso molecolare:400.53HSP90-IN-19
CAS:HSP90-IN-19: potent Hsp90 inhibitor, IC50 = 0.27 μM, used in research on viral diseases, neurodegeneration, inflammation.Formula:C29H38O7Purezza:98%Colore e forma:SolidPeso molecolare:498.61CYP1B1-IN-3
CAS:CYP1B1-IN-3: strong CYP1B1 inhibitor (IC50: 6.6 nM); weak on CYP1A1/CYP1A2; hinders cell migration, invasion; blocks P-gp, AKT/ERK, FAK/SRC, EMT.Formula:C20H16FN3O2S2Colore e forma:SolidPeso molecolare:413.49DNQX
CAS:<p>DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)</p>Formula:C8H4N4O6Purezza:97.27% - 99.1%Colore e forma:Off-White Powder With A Yellow TingePeso molecolare:252.14CYP1B1-IN-4
CAS:<p>CYP1B1-IN-4: 2,4-diarylthiazole, selective CYP1B1 inhibitor (IC50=0.2 nM), low cytotoxicity, stable in liver microsomes.</p>Formula:C18H14N2O2SPurezza:98.74%Colore e forma:SolidPeso molecolare:322.38CYP1B1-IN-5
CAS:CYP1B1-IN-5: selective CYP1B1 inhibitor, IC50 = 4.7 nM, useful for metabolism disease research.Formula:C14H8INO2Purezza:97.66%Colore e forma:SolidPeso molecolare:349.12HDAC6-IN-15
HDAC6-IN-15: selective HDAC6 inhibitor, IC50 of 38.2 nM, for cancer and neurodegenerative research.Formula:C25H28FFeN3O2Colore e forma:SolidPeso molecolare:477.35Urease-IN-4
<p>Urease-IN-4 inhibits urease (IC50: 1.64 µM), targets P. vulgaris (IC50: 15.27 µg/mL), and is low in cytotoxicity.</p>Formula:C16H20N2O3SColore e forma:SolidPeso molecolare:320.41Urease-IN-5
Urease-IN-5: urease inhibitor, IC50 1.473 µM, low cytotoxicity, IC50 17.78 µg/mL on P. vulgaris.Formula:C16H20N2O3SColore e forma:SolidPeso molecolare:320.41KIF18A-IN-6
CAS:KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor that suppresses KIF18A microtubule-dependent ATPase activity with an IC50 of 0.016 μM.Formula:C28H37N3O5S2Purezza:97.59%Peso molecolare:559.74JQEZ5
CAS:JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).Formula:C30H38N8O2Purezza:98.14% - ≥98%Colore e forma:SolidPeso molecolare:542.68KIF18A-IN-7
CAS:KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependentFormula:C27H35N3O5S2Colore e forma:SoildPeso molecolare:545.71Leritrelvir
CAS:<p>Dermatan sulphate sodium (Chondroitin sulfate B sodium salt) is a linear sulfated polysaccharide, a glycosaminoglycan component of important proteoglycans.</p>Formula:C31H44F3N5O6Purezza:97.42%Colore e forma:SolidPeso molecolare:639.71Pomotrelvir
CAS:<p>Pomotrelvir (PBI-0451) is an oral SARS-CoV-2 3CL protease inhibitor with antiviral properties for COVID-19 research.</p>Formula:C23H26ClN5O3Colore e forma:SolidPeso molecolare:455.94BAY 2965501
CAS:BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor that induces pERK activation.BAY 2965501 can be used in the study of cancer.Formula:C20H19FN4O3SPurezza:99.89%Colore e forma:SolidPeso molecolare:414.45Moiramide B
CAS:Moiramide B is an acetyl coenzyme A carboxylase inhibitor with antimicrobial activity, strongly inhibiting Gram-positive bacteria.Formula:C25H31N3O5Purezza:98.53% - 99.90%Colore e forma:SolidPeso molecolare:453.53(S)-VQW-765
(S)-VQW-765, oral α7 nAChR partial agonist, may improve cognition in Alzheimer's and schizophrenia.Formula:C19H22N2OColore e forma:SolidPeso molecolare:294.39Tiludronate
CAS:Tiludronate, an oral bisphosphonate, treats metabolic bone disorders and inhibits osteoclasts.Formula:C7H9ClO6P2SColore e forma:SolidPeso molecolare:318.61Cloxacillin
CAS:Cloxacillin, a β-lactamase inhibitor, tackles S. aureus inflammation and has an IC50 of 0.04 µM.Formula:C19H18ClN3O5SColore e forma:SolidPeso molecolare:435.88Acamprosate
CAS:Acamprosate, alcohol dependence treatment. Affordable Excellence: Reliable Quality You Can TrustFormula:C5H11NO4SPurezza:98.30%Colore e forma:SolidPeso molecolare:181.21Valorphin
CAS:Valorphin (Valorphin TFAsalt) has opioid analgesic activity, binds to rat mu-opioid receptor, with an IC50 of 14 nM.Formula:C44H61N9O11Purezza:98%Colore e forma:SolidPeso molecolare:892.01Pralidoxime
CAS:Pralidoxime reactivates AChE blocked by nerve agents, aiding as an organophosphate poisoning antidote.Formula:C7H9N2OColore e forma:SolidPeso molecolare:137.16Amakusamine
CAS:Amakusamine is an indole alkaloid from the sponge of Psammocinia sp. that inhibits RANKL-induced isolation of multinucleated osteoclast formation.Formula:C9H5Br2NO2Purezza:98.37% - 98.42%Colore e forma:SolidPeso molecolare:318.95Rostratin A
CAS:Rostratin A, a disulfide from Exserohilum rostratum, is cytotoxic to HCT-116 cells with an IC50 of 8.5 μg/mL.Formula:C18H24N2O6S2Colore e forma:SolidPeso molecolare:428.52Rostratin B
CAS:Rostratin B, a cytotoxic disulfide, demonstrates in vitro cytotoxicity against human colon carcinoma (HCT-116), exhibiting an IC50 value of 1.9 μg/mL.Formula:C18H20N2O6S2Colore e forma:SolidPeso molecolare:424.49Rostratin C
CAS:Rostratin C, a cytotoxic disulfide, exhibits in vitro cytotoxicity against human colon carcinoma (HCT-116), demonstrating an IC50 value of 0.76 μg/mL.Formula:C20H24N2O8S2Colore e forma:SolidPeso molecolare:484.54Thielavin B
CAS:Thielavin B, from Thielavia terricola, inhibits prostaglandin E2 synthesis and reduces rat oedema.Formula:C31H34O10Colore e forma:SolidPeso molecolare:566.6Isodispar B
CAS:Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.Formula:C20H18O5Colore e forma:SolidPeso molecolare:338.35Mammea A/BA
CAS:Mammea A/BA combats T. cruzi by causing mitochondrial damage, ROS, DNA fragmentation, and vacuolization, leading to cell death. Useful for Chagas research.Formula:C25H26O5Colore e forma:SolidPeso molecolare:406.47Kurzipene D
CAS:Kurzipene D: anticancer, induces apoptosis, halts HepG2 at S phase, anti-tumor in zebrafish, inhibits tumor growth and spread.Formula:C26H36O8Colore e forma:SolidPeso molecolare:476.56Vorasidenib
CAS:Vorasidenib (PVM/MA) is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)Formula:C14H13ClF6N6Purezza:98.28% - 99.57%Colore e forma:SolidPeso molecolare:414.74STAT3-IN-14
CAS:<p>STAT3-IN-14 is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 can directly bind to the hinge region of STAT3 .</p>Formula:C14H10O5Colore e forma:SolidPeso molecolare:258.23PTP1B-IN-20
PTP1B-IN-20: Selective PTP1B inhibitor, IC50=1.05μM; less effective on TCPTP (IC50=78μM), targets type 2 diabetes.Formula:C26H28O15Colore e forma:SolidPeso molecolare:580.49PTP1B-IN-21
PTP1B-IN-21 inhibits PTP1B (IC50=1.56μM) selectively over TCPTP, a type 2 diabetes target.Formula:C22H22O11Colore e forma:SolidPeso molecolare:462.4Phanginin A
CAS:Phanginin A, a natural product, activates SIK1 and inhibits gluconeogenesis in mouse primary hepatocytes, can be used in studies of type 2 diabetes.Formula:C21H28O5Purezza:95.54%Colore e forma:SolidPeso molecolare:360.44BACE1-IN-10
CAS:<p>BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].</p>Formula:C33H49N5O8SPurezza:98%Colore e forma:SolidPeso molecolare:675.84Nomifensine
CAS:Nomifensine ((±)-Nomifensin) is a norepinephrine-dopamine reuptake inhibitor that prevents dopamine reuptake into synaptosomes.Formula:C16H18N2Purezza:99.83% - ≥95%Colore e forma:SolidPeso molecolare:238.33(R)-V-0219
(R)-V-0219: GLP-1R PAM, orally active, triggers Ca++ flux in HEK-hGLP-1R cells.Formula:C20H25F3N4O2Colore e forma:SolidPeso molecolare:410.43(S)-V-0219
(S)-V-0219: oral, GLP-1R PAM, boosts calcium in hGLP-1R HEK cells, lowers glucose, curbs hunger in mice.Formula:C20H25F3N4O2Colore e forma:SolidPeso molecolare:410.43TES Sodium
CAS:TES sodium is an amphoteric ion buffer with an effective pH range of 6.8 to 8.2, commonly used in cell culture and enzyme studies.Formula:C6H15NNaO6SColore e forma:SolidPeso molecolare:252.24
