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BAY1125976
CAS:<p>BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)</p>Formula:C23H21N5OPurezza:99.28% - ≥98%Colore e forma:SolidPeso molecolare:383.45PI3K-IN-36
CAS:PI3K-IN-36 is a potent inhibitor of PI3K, suitable for research applications in follicular lymphoma (FL).Formula:C30H36F2N8OColore e forma:SolidPeso molecolare:562.66USP22-IN-1
CAS:<p>USP22-IN-1 is a ubiquitin-specific peptidase 22 (USP22) inhibitor that can be used to treat proliferative diseases or cancer.</p>Formula:C22H18N4Purezza:98.2%Colore e forma:SolidPeso molecolare:338.41SLU-PP-915
CAS:SLU-PP-915, ERR agonist, EC50 ~400 nM for ERRα/β/γ, may aid oxidative metabolism & heart health.Formula:C17H13BFNO3SColore e forma:SolidPeso molecolare:341.16EGFR-IN-69
CAS:EGFR-IN-69: Potent EGFR inhibitor for NSCLC research; IC50: 4.3-25.6 nM against various EGFR mutations.Formula:C31H37Cl2N7O3SColore e forma:SolidPeso molecolare:658.64EGFR-IN-70
EGFR-IN-70: potent EGFR inhibitor, IC50 of 23.6 nM (LR/TM/CS), 307.5 nM (WT), anti-proliferative, inhibits EGFR phosphorylation, for cancer research.Formula:C31H36ClN5O5SColore e forma:SolidPeso molecolare:626.17BMS-986339
CAS:BMS-986339: oral, potent FXR agonist; binds to His298/ASN287; for PBC, PSC, NASH, anti-fibrosis research.Formula:C35H41F4N3O4Colore e forma:SolidPeso molecolare:643.71LabMol-301
CAS:LabMol-301 blocks NS5 RdRp/NS2B-NS3pro (IC50: 0.8/7.4µM), protects cells from ZIKV death.Formula:C18H16N6Colore e forma:SolidPeso molecolare:316.36LY2828360
CAS:LY2828360: CB2 agonist, Ki=40.3 nM; biases CB2 over CB1 with EC50s of 20.1 nM and >100 μM.Formula:C22H27ClN6OPurezza:98.45% - 99.51%Colore e forma:SolidPeso molecolare:426.94HadAB-IN-1
CAS:HadAB-IN-1: potent TB research chemical; IC50 = 0.03μM; inhibits HadAB, affecting Mtb mycolic acid synthesis.Formula:C19H17BrClN3O3SColore e forma:SolidPeso molecolare:482.78CDK7-IN-20
CDK7-IN-20: potent, irreversible CDK7 inhibitor, IC50 of 4nM, 206x selectivity vs. other CDKs, potential for ADPKD study.Formula:C30H26N6O3Colore e forma:SolidPeso molecolare:518.57SOS1-IN-15
CAS:<p>SOS1-IN-15 is an orally active and potent SOS1 inhibitor with potential antitumor activity.SOS1-IN-15 is used in the study of colon cancer.</p>Formula:C28H27F3N6O2Purezza:98.32%Colore e forma:SolidPeso molecolare:536.548EGFR-IN-73
CAS:EGFR-IN-73 (Compound 3f) effectively inhibits the prevalent EGFR mutation, EGFR Del19, exhibiting an IC50 value of 119 nM [1].Formula:C19H17ClFN3O4Purezza:98%Colore e forma:SolidPeso molecolare:405.81FUBP1-IN-2
CAS:FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.Formula:C26H26ClN3O4Colore e forma:SolidPeso molecolare:479.96HDAC-IN-49
<p>HDAC-IN-49: potent, broad HDAC inhibitor; IC50s: 10-1880 nM for HDAC1-6; strong anti-leukemic, low toxicity to healthy cells.</p>Formula:C26H27FN4O4Colore e forma:SolidPeso molecolare:478.52CU-CPT-9a
CAS:<p>CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-</p>Formula:C17H15NO2Purezza:99.01%Colore e forma:SolidPeso molecolare:265.31EGFR-IN-74
EGFR-IN-74 is a potent inhibitor targeting EGFR, specifically effective against the L858R/T790M mutations, exhibiting an IC50 value of 138 nM.Formula:C32H28BrF3N6O4SColore e forma:SolidPeso molecolare:729.57FOXM1-IN-1
FOXM1-IN-1: Potent inhibitor of FOXM1, IC50=2.65µM, hinders cell growth & lowers FOXM1, PLK1, CDC25B levels.Formula:C23H30ClNO3Colore e forma:SolidPeso molecolare:403.94MMP-1-IN-1
MMP-1-IN-1 is a highly potent MMP-1 inhibitor with an IC 50 of 0.034 μM .Formula:C14H17ClN2O3Colore e forma:SolidPeso molecolare:296.75LRRK2-IN-7
CAS:LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.Formula:C24H26N6OPurezza:99.26%Colore e forma:SolidPeso molecolare:414.5hCAII-IN-9
CAS:<p>hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.</p>Formula:C15H16ClN3O5S2Purezza:98.63%Colore e forma:SolidPeso molecolare:417.89EGFR-IN-75
EGFR-IN-75 inhibits EGFR WT/T790M; IC50s: 0.28/5.02 μM. It has anticancer and antioxidant effects.Formula:C10H6N6S2Colore e forma:SolidPeso molecolare:274.32HDAC-IN-50
CAS:HDAC-IN-50, a potent FGFR/HDAC inhibitor (IC50: 0.18-13 nM), induces apoptosis, cell cycle arrest, and shows anti-tumor activity.Formula:C31H41N7O4Colore e forma:SolidPeso molecolare:575.7Elimusertib
CAS:Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy inFormula:C20H21N7OPurezza:98.72% - 99.84%Colore e forma:SolidPeso molecolare:375.43NSC 295642
CAS:<p>NSC 295642: phosphatase inhibitor, boosts phospho-Erk in cells, aids cancer research.</p>Formula:C15H14ClCuN3S2Colore e forma:SolidPeso molecolare:399.42HDAC-IN-51
HDAC-IN-51 is an HDAC inhibitor.Formula:C27H24N4O2Purezza:98.85%Colore e forma:SolidPeso molecolare:436.51BSJ-04-122
CAS:BSJ-04-122: MKK4/7 inhibitor with IC50s of 4 nM & 181 nM, used in cancer research.Formula:C15H12ClN5OPurezza:98.09%Colore e forma:SolidPeso molecolare:313.74SMYD3-IN-2
SMYD3-IN-2, a cancer research chemical, inhibits SMYD3 (IC50 0.81 μM) and BGC823 (IC50 0.75 μM), inducing fatal autophagy in gastric cancer.Formula:C26H21BrN2O4Colore e forma:SolidPeso molecolare:505.36BChE-IN-15
<p>BChE-IN-15 is a compound characterized as a pseudo-irreversible, covalent inhibitor of butyrylcholinesterase (BChE), demonstrating potent activity with an</p>Formula:C22H33N3O2Colore e forma:SolidPeso molecolare:371.52PRMT6-IN-3
CAS:PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells.Formula:C19H26N4O2SPurezza:98.12%Colore e forma:SolidPeso molecolare:374.5HPK1-IN-31
HPK1-IN-31 inhibitor with an IC 50 value of 0.8 nM. HPK1-IN-31 has anti-tumour activity and has great potential for immunotherapy .Formula:C30H33N7O3Colore e forma:SolidPeso molecolare:539.63BuChE-IN-7
<p>BuChE-IN-7: selective hBuChe & eqBuChe inhibitor, IC50s 40/80 nM, boosts cognition & memory, and penetrates blood-brain barrier.</p>Formula:C25H34N2O2Colore e forma:SolidPeso molecolare:394.55RK-0133114
RK-0133114, R-enantiomer of RK-701, is a G9a inhibitor (IC50 = 3.7 μM) for SCD research.Formula:C26H30N4O3Colore e forma:SolidPeso molecolare:446.54Ficonalkib
CAS:Ficonalkib is a potent antineoplastic agent that inhibits the Anaplastic Lymphoma Kinase (ALK) tyrosine kinase receptor.Formula:C29H39N7O3SColore e forma:SolidPeso molecolare:565.737-Methylguanosine
CAS:7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).Formula:C11H16N5O5Purezza:98.11%Colore e forma:SolidPeso molecolare:298.28Fulzerasib
CAS:<p>Fulzerasib is an orally active KRAS G12C inhibitor that covalently binds to cysteine residue on the protein, thereby inhibiting the growth of KRAS G12C mutant</p>Formula:C32H30ClFN6O4Purezza:98.04%Colore e forma:SolidPeso molecolare:617.07LONP1-IN-2
CAS:LONP1-IN-2: Potent LONP1 inhibitor, IC50=0.187μM; weak on 20S proteasome (>10μM); for cancer research.Formula:C16H27BN4O4Colore e forma:SolidPeso molecolare:350.22DOCK2-IN-1
CAS:<p>DOCK2-IN-1, a CPYPP analogue, inhibits DOCK2 (IC50=19.1μM), reversibly binds DHR-2, and suppresses lymphocyte chemotaxis and T cell activation.</p>Formula:C16H11ClN2O2Colore e forma:SolidPeso molecolare:298.72EAPB 02303
CAS:<p>EAPB 02303, a microtubule inhibitor, induces mitotic arrest, spindle impairment, apoptosis, and has antitumor effects, enhancing Paclitaxel.</p>Formula:C17H14N4O2Colore e forma:SolidPeso molecolare:306.32RGB-286638
CAS:RGB-286638 inhibits multiple CDKs and GSK-3β, TAK1, Jak2, MEK1 with IC50s as low as 1-54 nM.Formula:C29H37Cl2N7O4Colore e forma:SolidPeso molecolare:618.55Piperazine
CAS:<p>Piperazine (1,4-Diazacyclohexane), a gamma-aminobutyric acid (GABA) agonist, serves as a crucial building block and core component in a wide range of marketed drugs known for their varied pharmacological activities.</p>Formula:C4H10N2Colore e forma:SolidPeso molecolare:86.14Nifuroxime
CAS:Nifuroxime, an anti-infective agent, is utilized in researching fungal infections.Formula:C5H4N2O4Colore e forma:SolidPeso molecolare:156.1Yadanzigan
CAS:<p>Yadanzigan(YDZG),a specific NLRP3 inhibitor, attenuates the NF-κB pathway and reactive oxygen species generation, while enhancing TRIM31, anti-inflammatory.</p>Formula:C26H38O14Purezza:99.98%Colore e forma:SolidPeso molecolare:574.57Tozadenant
CAS:Tozadenant (SYN115) is an adenosine A2A receptor antagonist(Ki of 11.5 nM and 6 nM on human and rhesus,respectively)Formula:C19H26N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:406.5Stigmane B
<p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>Formula:C21H30O4Colore e forma:SolidPeso molecolare:346.46BChE-IN-11
CAS:BChE-IN-11: potent, selective, non-competitive BChE inhibitor; IC50=2.1μM; used in AD research.Formula:C22H18O4Colore e forma:SolidPeso molecolare:346.38Praelolide
Praelolide activates Nrf2, hinders osteoclastogenesis/ROS, binds Keap1 noncovalently, may aid bone disease research.Formula:C28H35ClO12Colore e forma:SolidPeso molecolare:599.02Wikstrol A
CAS:Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.Formula:C30H22O10Colore e forma:SolidPeso molecolare:542.49Laburnetin
CAS:Laburnetin: an isoflavone antibacterial, combats fungi/S. vesicarium, boosts MRSA methicillin susceptibility, used in pest control.Formula:C20H18O6Colore e forma:SolidPeso molecolare:354.35Olamkicept
CAS:Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.Purezza:98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Colore e forma:Liquid
