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CFT8634
CAS:CFT8634 degrades BRD9, for synovial sarcoma and SMARCB1 tumor research, from patent WO2021178920A1.Formula:C37H45F3N6O5Colore e forma:SolidPeso molecolare:710.79VT02956
CAS:<p>VT02956 inhibits LATS1 (IC50: 0.76 nM) & LATS2 (0.52 nM), targets Hippo pathway, and hampers ER+ breast cancer growth.</p>Formula:C22H23N5OColore e forma:SolidPeso molecolare:373.45PF-04979064
CAS:<p>PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).</p>Formula:C24H26N6O3Purezza:98.20% - ≥98%Colore e forma:SolidPeso molecolare:446.5KFU-127
KFU-127: broad-spectrum antimicrobial; targets bacterial/fungal biofilms; toxic to eukaryotic cells.Formula:C34H43BrN2O3Colore e forma:SolidPeso molecolare:607.62BAY-390
CAS:BAY-390, a selective TRPA1 inhibitor, crosses species, penetrates brains, with IC50s: 16-82 nM. Used in inflammation research.Formula:C13H15F4NOColore e forma:SolidPeso molecolare:277.26MS47134
MS47134: potent MRGPRX4 agonist, EC50 = 149 nM, for pain/itch/hypersensitivity research.Formula:C22H29NO3Colore e forma:SolidPeso molecolare:355.47BI-2081
CAS:<p>BI-2081: GPR40 agonist, EC50=4nM, boosts insulin, lowers blood glucose, potential for type 2 diabetes research.</p>Formula:C32H35FO6Colore e forma:SolidPeso molecolare:534.62BI-2540
CAS:BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .Formula:C24H15ClF5NO5Colore e forma:SolidPeso molecolare:527.83AK-IN-1
CAS:AK-IN-1: competitive adenosine inhibitor, not ATP; inhibits AK 86-89% at 2-10 µM; promising for ischaemia, inflammation, seizure research.Formula:C22H21N3O4Colore e forma:SolidPeso molecolare:391.42DP00477
CAS:DP00477, a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibits an inhibitory concentration (IC50) of 7.0 µM.Formula:C17H11ClF3N3OSColore e forma:SolidPeso molecolare:397.8MK-3402
CAS:<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Formula:C15H19N9O5S2Colore e forma:SolidPeso molecolare:469.50MPH-220
CAS:MPH-220: Oral myosin-2 inhibitor, induces muscle relaxation, useful for spasticity research.Formula:C20H21N3O3SColore e forma:SolidPeso molecolare:383.46SDMA
CAS:<p>SDMA (Symmetric dimethylarginine) is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal</p>Formula:C8H18N4O2Purezza:95.74% - ≥98%Colore e forma:SolidPeso molecolare:202.25ccc_R08
CAS:<p>ccc_R08 is an HBV cccDNA inhibitor that reduces extracellular levels of HBV DNA, HBsAg, and HBeAg. ccc_R08 may be investigated in HBV infections.</p>Formula:C22H19ClO6Purezza:99.45% - 99.86%Colore e forma:SoildPeso molecolare:414.84TBI-166
CAS:TBI-166, an oral riminophenazine, treats tuberculosis with fewer side effects than Clofazimine.Formula:C32H30F3N5O3Colore e forma:SolidPeso molecolare:589.61KM04416
CAS:<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Formula:C12H11NO3SPurezza:99.88%Colore e forma:SolidPeso molecolare:249.29STL1267
CAS:STL1267 is a REV-ERB agonist that crosses the blood-brain barrier and inhibits BMAL1 gene expression.Formula:C17H11ClN4OPurezza:99.19%Colore e forma:SolidPeso molecolare:322.75BRD7586
CAS:BRD7586 is a cell-permeable small molecule inhibitor of SpCas9 that enhances SpCas9 specificity.Formula:C17H14ClN3O3S2Purezza:97.70% - 99.03%Colore e forma:SolidPeso molecolare:407.89TIM-063
CAS:TIM-063: ATP-competitive CaMKKα/β inhibitor, cell-permeable, Ki: 0.35/0.2 μM, IC50: 0.63/0.96 μM.Formula:C18H9N3O4Colore e forma:SolidPeso molecolare:331.28BI-3231
CAS:<p>BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.</p>Formula:C16H14F2N4O3SPurezza:98.2%Colore e forma:SolidPeso molecolare:380.37NP10679
CAS:NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.Formula:C23H26F3N3O3Purezza:99.43%Colore e forma:SolidPeso molecolare:449.47CZS-241
CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.Formula:C26H24ClF2N9OColore e forma:SolidPeso molecolare:551.987-Hydroxy-4H-chromen-4-one
CAS:7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).Formula:C9H6O3Purezza:97.65%Colore e forma:SolidPeso molecolare:162.14TH-Z145
CAS:<p>TH-Z145 is a potent FPPS inhibitor for the study of myeloma and lung cancer.</p>Formula:C16H28O7P2Purezza:98.29%Colore e forma:SolidPeso molecolare:394.34BAY-364
CAS:BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+Formula:C23H19N3O4Colore e forma:SolidPeso molecolare:401.41MRS4596
MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.Formula:C21H14N5NaO3SColore e forma:SolidPeso molecolare:439.42MRS4719
CAS:<p>MRS4719: potent P2X4 antagonist, IC50 0.503 μM. Reduces infarct, brain atrophy, Ca2+ influx. Used in ischemic stroke research.</p>Formula:C26H13N5O3S·C6H15NColore e forma:SolidPeso molecolare:504.6SAHA-OH
CAS:SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.Formula:C15H22N2O4Purezza:98%Colore e forma:SolidPeso molecolare:294.35Ph-HTBA
CAS:Ph-HTBA: high-affinity CaMKIIα modulator, brain-penetrant, Kd 757 nM, used in ischemia/neurodegeneration research.Formula:C19H18O3Colore e forma:SolidPeso molecolare:294.34DRP1i27
CAS:DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.Formula:C20H26N6OColore e forma:SolidPeso molecolare:366.46DN-1289
<p>DN-1289: oral, BBB-penetrating, selectively inhibits DLK (IC50=17nM) & LZK (IC50=40nM), blocks p-c-Jun in mouse optic nerve crush.</p>Formula:C18H19F4N7O2Purezza:98.56%Colore e forma:SolidPeso molecolare:441.38LWG-301
LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.Formula:C28H38N8O3SColore e forma:SolidPeso molecolare:566.72DS-9300
CAS:DS-9300, an orally administered potent and selective inhibitor of EP300/CBP HAT, exhibits a significant inhibitory activity with an IC50 value of 28 nM.Formula:C25H26F3N5O3Colore e forma:SolidPeso molecolare:501.50Lodenafil
CAS:Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)Formula:C23H32N6O5SPurezza:99.92%Colore e forma:SolidPeso molecolare:504.6DDO3711
CAS:"DDO3711, a PHORC, links an ASK1 inhibitor to a PP5 activator, inhibiting ASK1 (IC50=164.1 nM), dephosphorylating p-ASK1, and showing anti-cancer potential."Formula:C42H41N9O6Colore e forma:SolidPeso molecolare:767.83BAY-805
CAS:BAY-805, a selective USP21 inhibitor, targets DUBs with high specificity.Formula:C24H28F3N5O2SPurezza:99.49%Colore e forma:SolidPeso molecolare:507.57MK-8189
CAS:MK-8189 is a potent and selective pyrimidine PDE10A inhibitor, with excellent PDE (phosphodiesterase) selectivity for the treatment of schizophrenia.Formula:C19H22N6OSPurezza:99.38% - 99.67%Colore e forma:SolidPeso molecolare:382.48(1R,2R)-MK-8189
CAS:(1R,2R)-MK-8189 is an isomer of MK-8189, a potent and selective pyrimidine PDE10A inhibitor.Formula:C19H22N6OSPurezza:>99.99% - >99.99%Colore e forma:SoildPeso molecolare:382.48NX-2127
CAS:NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferativeFormula:C39H45N9O5Purezza:99.07%Colore e forma:SolidPeso molecolare:719.83TYA-018
CAS:<p>TYA-018 is an HDAC6 inhibitor with cardioprotective effects and is used in the study of dilated heart disease and heart failure.</p>Formula:C15H13ClF2N4O3S2Purezza:98.64%Colore e forma:SolidPeso molecolare:434.87Goitrin
CAS:<p>Goitrin, from glucosinolate reactions, blocks thyroid peroxidase and iodine use, and fights H1N1.</p>Formula:C5H7NOSColore e forma:SolidPeso molecolare:129.18Pulixin
CAS:Pulixin blocks FREP1 from P. falciparum, hinders parasite spread (EC50: 11µM), and stops its growth (EC50: 47nM).Formula:C14H11NO4Colore e forma:SolidPeso molecolare:257.24SG2057
CAS:<p>SG2057 (DRG16), a PBD dimer with pentyldioxy linkage, binds DNA minor groove, forms cross-links, and is a potent antitumor agent.</p>Formula:C33H36N4O6Colore e forma:SolidPeso molecolare:584.66CU-CPT-8m
CAS:CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)Formula:C14H12N4OPurezza:99.00%Colore e forma:SolidPeso molecolare:252.27PF-184
PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.Formula:C32H32ClFN6O4Colore e forma:SolidPeso molecolare:619.09YLT-11
<p>YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.</p>Formula:C24H24N6OColore e forma:SolidPeso molecolare:412.49Erasin
Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.Formula:C20H19N3O3Colore e forma:SolidPeso molecolare:349.38TPN729
CAS:TPN729, a PDE5 inhibitor, has an IC50 of 2.28 nM, used to research erectile dysfunction.Formula:C25H36N6O4SColore e forma:SolidPeso molecolare:516.66SMN-C2
CAS:<p>SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.</p>Formula:C24H27N5O2Purezza:99.14%Colore e forma:SolidPeso molecolare:417.5YC-001
CAS:YC-001: inverse agonist/antagonist for rod opsin, prevents light-induced retinal degeneration.Formula:C12H7ClO2S2Colore e forma:SolidPeso molecolare:282.77
