CymitQuimica ha oltre 25 partner, tra i quali spicca il fornitore TargetMol
We have reached an agreement with TargetMol: CymitQuimica clients will benefit for a 20% discount on all TargetMol products until the end of the year.On our website you can find the products offered by this partner, which has become one of the world's most recognised compound libraries and small molecule inhibitors supplier. TargetMol offers approximately 120 compound libraries and a wide range of chemical products and kits for life sciences.
Finisce il 31 dic( 7 giorni restanti )
SMN-C2
CAS:<p>SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.</p>Formula:C24H27N5O2Purezza:99.14%Colore e forma:SolidPeso molecolare:417.5YC-001
CAS:YC-001: inverse agonist/antagonist for rod opsin, prevents light-induced retinal degeneration.Formula:C12H7ClO2S2Colore e forma:SolidPeso molecolare:282.77SHP844
CAS:SHP844: SHP2 inhibitor, IC50 18.9 µM, affects cell growth/survival by regulating tyrosine phosphorylation.Formula:C29H24ClN5O6Colore e forma:SolidPeso molecolare:573.98ME-143
CAS:ME-143, a 2nd-gen NADH oxidase inhibitor, blocks WNT/β-catenin pathway, active against various cancers in vitro/vivo.Formula:C21H18O4Colore e forma:SolidPeso molecolare:334.37JA2131
CAS:JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.Formula:C13H19N5O2S2Colore e forma:SolidPeso molecolare:341.45Imisopasem manganese
CAS:Imisopasem manganese (M40403) is a manganese superoxide MnSOD non-peptidyl mimetic.Formula:C21H35Cl2MnN5Purezza:98%Colore e forma:SolidPeso molecolare:483.38RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Formula:C41H78N8O5Colore e forma:SolidPeso molecolare:763.11ABD957
CAS:ABD957: covalent ABHD17 depalmitoylases inhibitor, IC50 0.21µM for ABHD17B, blocks N-Ras, halts NRAS-mutant AML cell growth.Formula:C27H36F3N7O5SColore e forma:SolidPeso molecolare:627.68AC-386
CAS:AC-386, a potent c-Met inhibitor (IC50 7.42 nM), inhibits cancer cell growth and aids anti-cancer resistance study.Formula:C35H34FN5O6Colore e forma:SolidPeso molecolare:639.67RMS-07
CAS:RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.Formula:C35H40N8O2Colore e forma:SolidPeso molecolare:604.74MC4343
<p>MC4343, a potent dual inhibitor targeting both EZH2 and histone deacetylase, presents promising potential for cancer research applications.</p>Formula:C36H41N5O4Colore e forma:SolidPeso molecolare:607.74BT-GSI
BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.Formula:C26H46BrN5O10P2Colore e forma:SolidPeso molecolare:730.52RIG012
CAS:RIG012 is a potent RIG-I inhibitor with an IC50 value of 0.71 μM measured by NADH-coupled ATPase.RIG012 inhibited the expression of IFN-β and ISG hRsad2.Formula:C23H21NO3Purezza:99.48%Colore e forma:SolidPeso molecolare:359.42Ralfinamide
CAS:Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.Formula:C17H19FN2O2Purezza:99.41%Colore e forma:SolidPeso molecolare:302.34MU1700
MU1700, an oral ALK1/2 inhibitor (IC50: 13/6 nM), has high cell and brain permeability.Formula:C26H22N4OColore e forma:SolidPeso molecolare:406.48TP-050
CAS:TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.Formula:C16H15ClF2N6OColore e forma:SolidPeso molecolare:380.78AB-836
CAS:AB-836, an orally active hepatitis B virus (HBV) capsid inhibitor, hampers viral replication by engaging with the HBV core protein.Formula:C20H15F3N4O2Colore e forma:SolidPeso molecolare:400.35RI-962
CAS:RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.Formula:C28H28N6O2Purezza:99.39%Colore e forma:SoildPeso molecolare:480.56TNG908
CAS:TNG908, a brain-penetrant PRMT5 inhibitor, is 15x more selective for MTAP mutant vs WT lines, useful in cancer studies.Formula:C21H23N5O2SPurezza:98.08% - 98.24%Colore e forma:SolidPeso molecolare:409.51q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Formula:C21H14O6S4Colore e forma:SolidPeso molecolare:490.59OUL232
CAS:OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.Formula:C10H10N4O2SPurezza:99.04%Colore e forma:SolidPeso molecolare:250.28GSK761
GSK761 inhibits SP140 (IC50: 77.79 nM), hinders monocyte-to-macrophage differentiation, and prompts CD206+ regulatory macrophages.Formula:C40H46N4O4Colore e forma:SolidPeso molecolare:646.82EG-011
CAS:EG-011, a potent first-in-class WASP activator, enhances actin polymerization, showing selective anti-tumor effects in lymphomas.Formula:C28H26N4O4Colore e forma:SolidPeso molecolare:482.53NG-497
CAS:<p>NG-497, a selective inhibitor of human ATGL, blocks lipolysis in adipocytes and aids cancer research.</p>Formula:C18H21NO4Purezza:99.56%Colore e forma:SolidPeso molecolare:315.36Nelotanserin
CAS:Nelotanserin (APD125): strong 5-HT2A inverse agonist (IC50: 1.7 nM), moderate 5-HT2C (79 nM), weak 5-HT2B (791 nM).Formula:C18H15BrF2N4O2Purezza:98.42% - 99.88%Colore e forma:SolidPeso molecolare:437.24AB-506
CAS:AB-506: Oral HBV replication blocker, targets core protein, hinders pgRNA encapsidation, for CHB study.Formula:C21H18ClF2N5O3Colore e forma:SolidPeso molecolare:461.85MC0704
MC0704: STAT3 inhibitor, IC50=2.13μM, promotes apoptosis & cell arrest, anti-breast cancer, for mTNBC research.Formula:C29H21BrN4O2Colore e forma:SolidPeso molecolare:537.41MR2938
CAS:MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.Formula:C21H24N4O3Colore e forma:SolidPeso molecolare:380.44GY1-22
CAS:GY1-22, an inhibitor targeting the DNAJA1-mutP53 R175H interaction pocket, holds potential for cancer research applications.Formula:C23H20N4OSColore e forma:SolidPeso molecolare:400.5TH-Z93
CAS:TH-Z93 is a potent FPPS inhibitor (IC50:90 nM) and a lipophilic bisphosphonate.Formula:C12H22N2O7P2Purezza:98.37%Colore e forma:SolidPeso molecolare:368.26NS1219
CAS:<p>NS1219, an isomer of NS1209, is a selective AMPA antagonist for studying stroke, neuropathic pain, and epilepsy.</p>Formula:C24H28N4O7SColore e forma:SolidPeso molecolare:516.57FLDP-5
CAS:FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.Formula:C21H21NO5Colore e forma:SolidPeso molecolare:367.4FLDP-8
CAS:FLDP-8, a curcuminoid analogue, exhibits potent anti-cancer properties by inducing cell death in LN-18 cells at an IC50 value of 4 μM.Formula:C22H23NO5Colore e forma:SolidPeso molecolare:381.423-Methylcytidine
CAS:<p>3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.</p>Formula:C10H15N3O5Purezza:99.52%Colore e forma:SolidPeso molecolare:257.24ZG1077
CAS:ZG1077, a covalent KRAS G12C inhibitor, is utilized in non-small cell lung cancer (NSCLC) research.Formula:C33H33F2N5O5SColore e forma:SolidPeso molecolare:649.71SZM679
SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.Formula:C27H18F5N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:591.51ZC0109
ZC0109 inhibits IDO1 (50 nM) & TrxR1 (3.0 μM), induces ROS, arrests G1/S phase, causing cancer cell apoptosis.Formula:C22H20BrFN8O4SColore e forma:SolidPeso molecolare:591.41YL-939
YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.Formula:C25H26N6OColore e forma:SolidPeso molecolare:426.51MC2590
CAS:MC2590 is a histone deacetylase (HDAC) inhibitor that inhibits HDAC1-3, -6, -8, and -10 activities, induces cell cycle arrest, and promotes apoptosis.Formula:C20H17N3O3Purezza:99.64%Colore e forma:SolidPeso molecolare:347.37EVT801
CAS:EVT801 is a highly selective and low-toxic VEGFR-3 inhibitor that inhibits VEGF-C-induced tumor lymphoid and angiogenesis and reduces CCL4, CCL5 and MDSC.Formula:C19H21N5O3Purezza:97.4%Colore e forma:SolidPeso molecolare:367.4RK-701
CAS:RK-701: G9a inhibitor, IC50 23-27 nM, increases HbF/γ-Globin/BGLT3, decreases H3K9me2, inhibits BCL11A/ZBTB7A.Formula:C26H30N4O3Colore e forma:SolidPeso molecolare:446.54FX-909
CAS:FX-909 is a covalent peroxisome proliferator-activated receptor gamma ( PPARG ) inverse agonist. FX-909 can be used for the research of cancer .Formula:C17H10F2N2O3SColore e forma:SolidPeso molecolare:360.33Pridopidine
CAS:Pridopidine (FR310826), a low-affinity D2R antagonist, enhances motor skills and has neuroprotective effects in Huntington's R6/2 mice.Formula:C15H23NO2SPurezza:95.2% - 99.89%Colore e forma:SolidPeso molecolare:281.41TNG260
TNG260: CoreDAC inhibitor, 10x more selective for HDAC1 over HDAC3, reverses anti-PD1 resistance, cuts neutrophil infiltration, enables immune cell killing.Formula:C20H18FN3O2SColore e forma:SolidPeso molecolare:383.44Nec-3a
CAS:Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.Formula:C21H18F4N2O4Colore e forma:SolidPeso molecolare:438.37OUL245
CAS:<p>OUL245: A selective PARP2 inhibitor (IC50=44nM), also inhibits other PARPs/TNKS (IC50=2.9-8.8μM).</p>Formula:C8H5N3OSColore e forma:SolidPeso molecolare:191.21XZ426
CAS:XZ426 is a potent integrase strand transfer inhibitor with anti- HIV activity .Formula:C22H24F2N4O4Colore e forma:SolidPeso molecolare:446.45ML202
CAS:ML202 activates human pyruvate kinase M2, affecting PEP cooperativity with minimal impact on ADP binding.Formula:C18H17N3O3S2Colore e forma:SolidPeso molecolare:387.48M5N36
CAS:M5N36: selective Cdc25C inhibitor, IC50: 0.15µM A, 0.19µM B, 0.06µM C; halts cell growth, boosts p-CDK1/2.Formula:C20H16ClN5O3Colore e forma:SolidPeso molecolare:409.83GK563
CAS:GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.Formula:C16H22O2Colore e forma:SolidPeso molecolare:246.34
