CymitQuimica ha oltre 25 partner, tra i quali spicca il fornitore TargetMol
We have reached an agreement with TargetMol: CymitQuimica clients will benefit for a 20% discount on all TargetMol products until the end of the year.On our website you can find the products offered by this partner, which has become one of the world's most recognised compound libraries and small molecule inhibitors supplier. TargetMol offers approximately 120 compound libraries and a wide range of chemical products and kits for life sciences.
Finisce il 31 dic( 7 giorni restanti )
Talotrexin
CAS:Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.Formula:C27H27N9O6Colore e forma:SolidPeso molecolare:573.56Mavodelpar
CAS:Mavodelpar (REN001), a PPARδ agonist, may treat PMM and LC-FAOD by reducing renal damage.Formula:C31H29FNNaO5Colore e forma:SolidPeso molecolare:537.55TAS-103 dihydrochloride
CAS:<p>TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.</p>Formula:C20H21Cl2N3O2Purezza:97.78%Colore e forma:SolidPeso molecolare:406.31EphB1-IN-1
CAS:EphB1-IN-1 is a potent inhibitor of EphB1, exhibiting IC50 values of 3.0 nM for EphB1 G703C, 15 nM for EphB1 T697G, and 220 nM for EphB1 WT.Formula:C16H12Cl2N4O2Colore e forma:SolidPeso molecolare:363.2NBI-921352
CAS:NBI-921352 (XEN901) is a potent NaV1.6 sodium channel inhibitor, effectively treating epilepsy without severe side effects.Formula:C22H25FN4O2S2Purezza:98%Colore e forma:SolidPeso molecolare:460.59Udifitimod
CAS:Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.Formula:C25H33NO2Colore e forma:SolidPeso molecolare:379.54Z-VRPR-FMK
CAS:Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.Formula:C31H49FN10O6Colore e forma:SolidPeso molecolare:676.78Adhesamine
CAS:Adhesamine, a dumbbell molecule, enhances cell adhesion, growth, neuron differentiation, and survival via MAPK/FAK.Formula:C24H32Cl4N8O2S2Colore e forma:SolidPeso molecolare:670.51PNU-101603
CAS:<p>PNU-101603, a Sutezolid metabolite, effective against TB including drug-resistant strains, works solo or with SQ109.</p>Formula:C16H20FN3O4SColore e forma:SolidPeso molecolare:369.41Z-LEVD-FMK
CAS:Z-LEVD-FMK is a caspase-4 inhibitor with anti-cancer activity, capable of eliminating LPS-induced GCLC protein degradation.Formula:C31H45FN4O10Colore e forma:SolidPeso molecolare:652.71SID-852843
CAS:SID-852843, WNV NS2B-NS3 protease inhibitor, IC50: 0.105 μM, useful in viral infection studies.Formula:C17H15N3O5SPurezza:99.59%Colore e forma:SolidPeso molecolare:373.38BACE2-IN-1
CAS:<p>BACE2-IN-1, a potent BACE2 inhibitor characterized by its exceptional selectivity and a Ki value of 1.6 nM, is utilized in the investigation of Type 2 Diabetes.</p>Formula:C36H38F3N3O3Colore e forma:SolidPeso molecolare:617.7Etbicyphat
CAS:Etbicyphat: potent GABA(A) antagonist, induces epileptiform activity, binds to GABA/benzodiazepine receptors.Formula:C6H11O4PColore e forma:SolidPeso molecolare:178.12Paquinimod
CAS:Paquinimod (ABR 25757) is a S100A9 inhibitor preventing S100A9 binding to TLR-4.Formula:C21H22N2O3Purezza:98.04% - 99.79%Colore e forma:SolidPeso molecolare:350.41ACT-606559
ACT-606559, a metabolite of ACT451840, is a novel chemical compound exhibiting antimalarial properties. It is utilized in malaria research.Formula:C47H52N6O3Colore e forma:SolidPeso molecolare:748.95EGFR-IN-25
CAS:EGFR-IN-25, an efficacious EGFR inhibitor, demonstrates IC50 values of 9 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and 60 nM for A431 cells (WT), respectively.Formula:C34H43N9O2Colore e forma:SolidPeso molecolare:609.76EGFR-IN-21
CAS:EGFR-IN-21, a potent EGFR inhibitor, exhibits an IC50 of 0.38 nM, demonstrating significant antitumor activity.Formula:C36H44BrN10O2PColore e forma:SolidPeso molecolare:759.68EGFR-IN-23
CAS:EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.Formula:C36H44BrN10O3PColore e forma:SolidPeso molecolare:775.68EGFR-IN-28
CAS:EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity .Formula:C31H39BrN10O3SColore e forma:SolidPeso molecolare:711.68EGFR-IN-29
CAS:EGFR-IN-29 is a potent EGFR inhibitor.Formula:C36H46BrN8O2PColore e forma:SolidPeso molecolare:733.68RAD51-IN-4
CAS:RAD51-IN-4, a potent RAD51 inhibitor, may be useful in researching mitochondrial defect-related conditions.Formula:C31H34FN5O5S2Colore e forma:SolidPeso molecolare:639.76EGFR-IN-30
CAS:EGFR-IN-30 is an EGFR inhibitor (IC50: 1-10 nM, <1 nM WT/mutants) with potential in cancer research.Formula:C28H33BrN7O2PColore e forma:SolidPeso molecolare:610.49JNK-1-IN-1
CAS:JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM.Formula:C24H22N6SColore e forma:SolidPeso molecolare:426.54Oxyphenisatin acetate
CAS:<p>Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468.</p>Formula:C24H19NO5Purezza:98% - 99.35%Colore e forma:SolidPeso molecolare:401.41PI3Ka-IN-5
CAS:PI3Ka-IN-5 is a potent PI3Kα/mTOR inhibitor, with an IC 50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer .Formula:C30H35N9O5Colore e forma:SolidPeso molecolare:601.66IDO1-IN-17
CAS:IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC 50 of 0.44 μM in hela cells .Formula:C28H32BrClFN5O2Colore e forma:SolidPeso molecolare:604.94STAT3-IN-7
CAS:STAT3-IN-7, an orally active aryl sulfonamido azetidine compound, serves as a STAT3 inhibitor with anticancer activities.Formula:C30H26F5N5O4SColore e forma:SolidPeso molecolare:647.62(S)-HH2853
CAS:(S)-HH2853 is a potent EZH1/2 inhibitor, aromatic, <100 nM IC50 for EZH2_Y641F, promising for anti-tumor/autoimmune research.Formula:C31H36F3N7O3Purezza:97.18% - 99.74%Colore e forma:SolidPeso molecolare:611.66(R)-HH2853
CAS:(R)-HH2853, a mutant EZH2 inhibitor, IC50 <100 nM for EZH2-Y641F, targets cancer/autoimmune diseases.Formula:C31H36F3N7O3Purezza:97.53% - 98.85%Colore e forma:SolidPeso molecolare:611.66ROCK2-IN-5
ROCK2-IN-5, a compound blending fasudil, caffeic, and ferulic acids, shows promise for ALS research involving SOD1 mutations.Formula:C23H25N3O5SColore e forma:SolidPeso molecolare:455.53PI3K-IN-28
CAS:PI3K-IN-28, a potent PI3K inhibitor with low toxicity in MCF-10a, has IC50 values of 5.8, 2.3, 7.9 μM and high selectivity index of 39.Formula:C26H16F9N3O3S2Colore e forma:SolidPeso molecolare:653.54AX20017
CAS:AX20017 is a small-molecule protein kinase G (PknG) inhibitor(IC50 : 0.39 μM). It acts by blocking the proliferation of M. tuberculosis.Formula:C13H16N2O2SPurezza:99.31%Colore e forma:SolidPeso molecolare:264.34MptpB-IN-1
CAS:MptpB-IN-1: orally active, potent MptpB inhibitor; reduces drug-resistant tuberculosis.Formula:C17H11Cl2NO4Colore e forma:SolidPeso molecolare:364.18FGFR4-IN-8
CAS:FGFR4-IN-8 is a selective, ATP-competitive FGFR4 inhibitor with IC50s as low as 0.25 nM, halting growth of Hep3B cells at 29 nM and showing in vivo efficacy.Formula:C32H34Cl2FN7O3Purezza:98%Colore e forma:SolidPeso molecolare:654.56ThrRS-IN-3
ThrRS-IN-3: Potent inhibitor of Salmonella enterica ThrRS, IC50 = 19 nM, Kd = 34 nM, with antibacterial effects.Formula:C31H30Cl2N6O5Colore e forma:SolidPeso molecolare:637.51SMTIN-T140
CAS:SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Formula:C36H34BrClFN5OPPurezza:98%Colore e forma:SolidPeso molecolare:718.02C16-K-cBB1
C16-K-cBB1: potent, selective MRSA killer; MIC 1µg/mL, low hemolysis, works in 120 min at 12.5µg/mL.Formula:C33H58ClN5O5SColore e forma:SolidPeso molecolare:672.36EGFR-IN-61
CAS:EGFR-IN-61 inhibits EGFR kinase (IC50: 42 nM L858R/T790M, 137 nM L858R/T790M/C797S, 743 nM WT) and slows A549 & H1975 cell growth (IC50: 2.14 & 1.82 μM).Formula:C33H37ClN8O3Purezza:98%Colore e forma:SolidPeso molecolare:629.15STAT6-IN-1
CAS:STAT6-IN-1: STAT6 inhibitor, IC50=0.028 µM, targets SH2 domain, for allergy and cancer research.Formula:C33H37IN3O7PColore e forma:SolidPeso molecolare:745.54Enclomiphene citrate
CAS:Enclomiphene citrate (trans-Clomiphene citrate) is a non-steroidal estrogen receptor antagonist,with antioestrogenic propertyFormula:C32H36ClNO8Purezza:99.95%Colore e forma:SolidPeso molecolare:598.08Mebanazine
CAS:<p>Mebanazine, a potent monoamine oxidase (MAO) inhibitor, is utilized in depression research.</p>Formula:C8H12N2Colore e forma:SolidPeso molecolare:136.19DS69910557
DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.Formula:C32H33Cl2FN4O3Colore e forma:SolidPeso molecolare:611.53FGF22-IN-1
CAS:<p>FGF22-IN-1 is a CD4 N-terminal immunoglobulin variable region-like structural domain (CD4 D1) inhibitor that suppresses the immune response.</p>Formula:C14H11N3OSPurezza:99.18%Colore e forma:SolidPeso molecolare:269.32EZH2-IN-14
CAS:<p>EZH2-IN-14 selectively inhibits EZH2 at 12 nM IC50, has >200-fold specificity over EZH1, reducing H3K27me3 levels.</p>Formula:C31H39N7O2Colore e forma:SolidPeso molecolare:541.69USP7-IN-10
CAS:<p>USP7-IN-10 is a potent inhibitor of ubiquitin-specific protease 7 (USP7), exhibiting an inhibition concentration half-maximal (IC50) value of 13.39 nM.</p>Formula:C26H29ClN4O3SColore e forma:SolidPeso molecolare:513.05MAT2A-IN-9
CAS:<p>MAT2A-IN-9, a 2-oxoquinazoline, inhibits MAT2A with antitumor effects on lymphomas and solid cancers.</p>Formula:C14H8ClF3N4OPurezza:99.17%Colore e forma:SolidPeso molecolare:340.69GSK1790627
CAS:GSK1790627, the N-deacetylated metabolite of Trametinib, represents an orally active MEK inhibitor that promotes autophagy and triggers apoptosis [1].Formula:C24H21FIN5O3Colore e forma:SolidPeso molecolare:573.36FLT3-IN-18
CAS:FLT3-IN-18: potent, selective FLT3 inhibitor, IC50 0.003 μM, induces apoptosis, G1 arrest, blocks FLT3/STAT5, potential in AML research.Formula:C26H36N8OColore e forma:SolidPeso molecolare:476.62PHGDH-IN-3
CAS:PHGDH-IN-3, an oral PHGDH blocker with 2.8 μM IC50, may help in cancer research.Formula:C24H18FN3O4S2Purezza:97.24% - 99.1%Colore e forma:SolidPeso molecolare:495.55FGFR3-IN-4
CAS:FGFR3-IN-4 is a selective inhibitor targeting FGFR3, demonstrating an IC50 value of under 50 nM.Formula:C26H24ClN7OColore e forma:SolidPeso molecolare:485.97
