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Main pharmacopeia reference standards gathered in CymitQuimica

Main pharmacopeia reference standards gathered in CymitQuimica

At CymitQuimica we have collected the standards you need from the most prestigious Pharmacopoeias:

These products are mainly used in Quality Control and R&D laboratories. From these standards and following the instructions in the monographs or chapters of each Pharmacopoeia, a product can be quantified or identified.

History of pharmacopoeias
Pharmacopoeias were originally compilation books of recipes for products with medicinal properties, including elements of their composition and preparation instructions.

The oldest known pharmacopoeias date back to ancient Egypt, although the publication of the 5-volume work "De materia medica" by the Greek Dioscorides (1st century) is usually considered to be the first pharmacopoeia. The work describes about 600 medicinal plants, about 90 minerals and about 30 substances of animal origin with medicinal properties, as well as the pathology to which they can be applied.

Modern pharmacopoeias consist of a set of monographs on analytical procedures, specifications for the synthesis and quality control of medicinal products, excipients and active ingredients of medicinal products. The indications of pharmacopoeias usually become legally binding requirements for companies wishing to market their pharmaceutical products. According to the World Health Organisation, there are currently 40 pharmacopoeias, and 60 commissions responsible for maintaining and developing them. The WHO itself publishes a pharmacopoeia that WHO member countries can integrate in their respective countries.

Among the pharmacopoeias, those corresponding to countries with an important pharmaceutical industry and relevant drug R&D activity stand out. The main pharmacopoeias include the United States Pharmacopeia, the European Pharmacopoeia, the British Pharmacopoeia and the Japanese Pharmacopoeia.

Pharmacopoeias define pharmacopoeia standards which are those chemical substances that are used in the analytical methods described in the pharmacopoeia. Pharmacopoeia standards usually have the following characteristics:

1.- High purity level
2.- Chemical stability (low reactivity)
3.- Low hygroscopicity capacity (to minimise weight changes with moisture).
4.- High relative mass (to minimise weighing errors).
5.- Low toxicity
6.- Easy and cheap to synthesise

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