L-2-Oxothiazolidine-4-carboxylic acid

CAS: 19771-63-2

Ref. 01-4012415

Product Information

• Name: L-2-Oxothiazolidine-4-carboxylic acid
• Synonyms: OTC, (-)-2-Oxo-4-thiazolidinecarboxylic acid, (4R)-2-Oxo-1,3-thiazolidine-4-carboxylic acid, (4R)-2-Oxo-4-thiazolidinecarboxylic acid, (4R)-2-Oxothiazolidine-4-carboxylic acid, (R)-(-)-2-Oxothiazolidine-4-carboxylic acid, 2-Oxo-<span class="text-smallcaps">L</span>-thiazolidine-4-carboxylic acid, 4-Thiazolidinecarboxylic acid, 2-oxo-, (4R)-, 4-Thiazolidinecarboxylic acid, 2-oxo-, (R)-, 4-Thiazolidinecarboxylic acid, 2-oxo-, <span class="text-smallcaps">L</span>-, <span class="text-smallcaps">L</span>-2-Oxo-4-thiazolidinecarboxylic acid, L-(-)-2-Oxo-4-thiazolidinecarboxylic Acid, L-2-Thiazolidinone-4-carboxylic acid, R-2-Oxo-1,3-thiazolidine-4-carboxylic acid
• CAS: 19771-63-2

Description

A strong antioxidant and a cysteine prodrug. OTC, a 5-oxoproline analog, is metabolized by 5-oxoprolinase and converted to cysteine, the rate-limiting amino acid for glutathione synthesis. It may therefore be useful in restoring depleted glutathione stores in HIV-1-infected persons, which may in turn inhibit the progression of HIV disease. OTC may be inserted in place of Pyr. The chemical behaviour of OTC was studied by MacLaren. OTC was employed in the total synthesis of Latrunculin A.

• Brand: Bachem

Chemical properties

• Molecular weight: 147.16
• Formula: C₄H₅NO₃S
• Purity: > 99%
• Color/Form: White Powder