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2-Chlorotrityl chloride resin (200-400 mesh, 1.5-1.9 mmol/g)
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2-Chlorotrityl chloride resin (200-400 mesh, 1.5-1.9 mmol/g)

CAS: 934816-82-7

Ref. 01-4025425

5g
153.00 €
25g
590.00 €
Estimated delivery in United States, on Tuesday 12 Dec 2023

Product Information

Name:
2-Chlorotrityl chloride resin (200-400 mesh, 1.5-1.9 mmol/g)
Synonyms:
  • 2-ClTrt resin
Description:

A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc-strategy. ClTrt resin is in particular suitable for the preparation of C-terminal prolyl and cysteinyl peptides (please see 2-Chlorotrityl Chloride Resin-Linked Amino Acids). Release from this resin is achieved by using 1-50 % TFA in CH2Cl2 containing 8 % triisopropylsilane, AcOH/CF3CH2OH/CH2Cl2, 0.5 % TFA or hexafluoroisopropanol/CH2Cl2. ClTrt resin has been used in cyclization reactions under Heck reaction conditions, the solid phase synthesis of b-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones and in Mannich reactions of alkynes, secondary amines and aldehydes in the presence of a copper (I) salt affording the corresponding aminomethylalkynyl adducts. 2-Chlorotrityl resin is highly suitable for the synthesis of peptide alcohols, e.g., peptaibols, and peptide o-aminoalkylamides.

Brand:
Bachem
Long term storage:
Notes:

Chemical properties

Molecular weight:
n/a
Formula:
na
Color/Form:
Light Yellow
MDL:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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