Product Information
- FN-439
- p-Aminobenzyl-Gly-Pro-D-Leu-D-Ala Hydroxamic acid
- N-[(4-aminophenyl)carbonyl]glycyl-L-prolyl-D-leucyl-N-hydroxy-D-alaninamide
- MMP Inhibitor I
The water-soluble peptidylhydroxamic acid FN439 is a broad-spectrum inhibitor of human matrix metalloproteinases. 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH retains its activity even after prolonged incubation with pronase or human granulocyte elastase. FN 439 inhibits interstitial and granulocyte collagenases, granulocyte gelatinase and skin fibroblast stromelysin with IC50 of 1 · 10-6 M, 3 · 10-5 M and 1.5 · 10-4 M, respectively.
Chemical properties
Technical inquiry about: 01-4025806 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH
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