Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
Ac-DEVD-CHO is a potent inhibitor of the poly(ADP-ribose) polymerase (PARP) cleavage by caspase-3 (IC50 = 0.2 nM). PARP cleavage occurs at the onset of apoptosis. The peptide aldehyde was able to attenuate apoptotic events in vitro (IC50 = 10 to 100 nM).
Technical inquiry about: 01-4026022 Ac-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
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