Product Information
Name:H-His-Cys-Lys-Phe-Trp-Trp-OH
Brand:Bachem
Description:HCKFWW, potent inhibitor of the HIV-encoded integrase (IN), the enzyme responsible for the integration of HIV DNA into the human genome. HCKFWW inhibits IN-mediated 3’processing and integration with an IC₅₀ of 2 µM. The peptide is also active on IN proteins from other retroviruses such as HIV-2, feline immunodeficiency virus and Moloney murine leukemia virus. It was also found to inhibit the disintegration reaction, suggesting that this hexapeptide acts at or near the catalytic site of IN.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:906.08
Formula:C46H55N11O7S
Purity:97.9%
Color/Form:White Lyophilisate
Technical inquiry about: H-His-Cys-Lys-Phe-Trp-Trp-OH
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