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Z-Val-Ala-DL-Asp-fluoromethylketone
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Z-Val-Ala-DL-Asp-fluoromethylketone

CAS: 220644-02-0

Ref. 01-4026865

5mg
300.00 €Add to cart
25mg
1,064.00 €Add to cart
Estimated delivery in United States, on Wednesday 24 Aug 2022

Product Information

Name:
Z-Val-Ala-DL-Asp-fluoromethylketone
Synonyms:
  • Z-VAD-FMK
  • L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-
  • L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-, (S)-
  • N-[(Benzyloxy)carbonyl]-L-valyl-N-(1-carboxy-4-fluoro-3-oxobutan-2-yl)-L-alaninamide
Description:

zVAD-FMK inhibited apoptosis induced by diverse stimuli. Preincubation of cells with this caspase-1 (ICE) inhibitor (50 uM) almost completely inhibited the formation of large kilobase-pair fragments of DNA, a characteristic biochemical change associated with apoptosis. Z-VAD-FMK was shown to irreversibly inhibit most types of caspases, hence it is also called pan-caspase inhibitor. For a cell-permeable analog see N-1560. Inhibitor of peptide:N-glycanase (PNGase).

Long term storage:
Notes:

Chemical properties

Molecular weight:
453.47
Formula:
C21H28FN3O7
Purity:
95.0%
Color/Form:
Beige Lyophilisate
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
GHS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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