Product Information
- (Glp1)-Apelin-13, human, bovine
- (Pyr1)apelin-13
- (pGlu1)apelin-13
- Pyr-apelin-13
- L-Phenylalanine,5-oxo-L-prolyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-
- Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
The pyroglutamyl form of apelin-13 exhibited a high activity with an EC₅₀ value of 0.30 nM. pERPRLSHKGPMPF is probably the final product of the post-translational modification of apelin and the biologically active endogenous ligand. (Pyr¹)-Apelin-13 has been identified as the predominant apelin isoform in the human heart. Pyr-Apelin-13 stimulates glucose utilization in normal and obese insulin-resistant mice. It could be required for the maintenance of insulin sensitivity.
Chemical properties
Technical inquiry about: 01-4029110 (Pyr¹)-Apelin-13 (human, bovine, mouse, rat)
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