Product Information
Name:Fmoc-Asp(OtBu)-(Hmb)Gly-OH
Synonyms:
- Fmoc-Asp(OtBu)-N-(2-hydroxy-4-methoxy-Bzl)-Gly-OH
Brand:Bachem
Description:Aspartimide formation of the highly base-labile Asp-Gly motif during Fmoc-SPPS may be completely suppressed by coupling this Hmb-protected dipeptide derivative. Additionally, Hmb prevents aggregation of the growing peptide chain as efficiently as the incorporation of a pseudoproline moiety. O-Acylation renders the Hmb moiety acid-stable facilitating the purification of peptides prone to form aggregates. The acyl group can be removed with hydrazine hydrate in DMF (cf. Quibell).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:604.67
Formula:C33H36N2O9
Purity:99.6%
Color/Form:White
Technical inquiry about: Fmoc-Asp(OtBu)-(Hmb)Gly-OH
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