- (Phe¹,Ser²,Tyr⁶)-Proteinase Activated Receptor 1 (1-6) amide (human), FSLLRYamide, (Phe¹,Ser²,Tyr⁶)-Thrombin Receptor (1-6) amide (human), (Phe¹,Ser²,Tyr⁶)-Coagulation Factor II Receptor (1-6) amide (mouse)
PAR-2 antagonist. FSLLRY-amide inhibited activation of PAR-2 by trypsin in PAR-2 receptor expressing KNRK cells. Half-maximal inhibition of calcium signaling was observed at about 50 uM. In contrast, the activation of PAR-2 by SLIGRL-amide was not inhibited by FSLLRY-amide.
Technical inquiry about: 01-4041474 (Phe¹,Ser²,Tyr⁶)-PAR-1 (1-6) amide (human)
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