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LL-37
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LL-37

CAS: 154947-66-7

Ref. 01-4042456

1mg
242.00 €Add to cart
5mg
678.00 €Add to cart
Estimated delivery in United States, on Monday 22 Aug 2022

Product Information

Name:
LL-37
Synonyms:
  • LL37, Antibacterial Protein LL-37 (human), CAMP
  • H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH
  • antibacterial protein LL-37 amide
Description:

LL-37 is an antimicrobial peptide with angiogenic activity. It corresponds to the C-terminal sequence (134-170) of the human cathelicidin antimicrobial protein hCAP18/LL-37 and is extracellularly released from hCAP18/LL-37 by proteolytic processing. hCAP18/LL-37 is an effector of the innate immune system and is expressed in leukocytes and epithelial cells where it is upregulated in association with inflammation and injury. An overexpression of hCAP18/LL-37 in a series of breast carcinomas could be demonstrated. LL-37 has been suggested to stimulate epithelial cell proliferation partially through formyl peptide receptor-like 1 (FPRL1) since blocking the receptor with pertussis toxin decreased the proliferative effect of LL-37 by approximately 50 %.

Long term storage:
Notes:

Chemical properties

Molecular weight:
4493.33
Formula:
C205H340N60O53
Purity:
96.7%
Color/Form:
White
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
GHS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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