Galanin-Like Peptide (rat)
- GALP (rat)
- 16: PN:WO0177166 SEQID: 15 claimed protein
- 2: PN: JP2000270871 SEQID: 2 claimedprotein
- GALP (Rattus norvegicus)
- GALP (galanin-like peptide) (rathypothalamus)
- PN: WO9948920 SEQID: 33 claimed protein
- Peptide (rat 60-aminoacid)
- Galanin-Like Peptide (Rat)
Galanin-like peptide (GALP), first isolated from the porcine hypothalamus and subsequently also identified in rats and humans, is a 60 amino acid neuropeptide that unlike galanin, has a non-amidated C-terminus. Its amino acid residues (9-21) are identical to the biologically active N-terminal (1-13) fragment of galanin. In contrast to galanin which is relatively non-selective, receptor binding studies revealed that GALP had a high affinity for the galanin receptor 2 (GALR2) and a lower affinity for the GALR1 receptor. Furthermore, it could be demonstrated that GALP stimulates food intake with a ten fold higher orexigenic activity than galanin and may also affect emotional state in the CNS.
Technical inquiry about: 01-4047028 Galanin-Like Peptide (rat)
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