Product Information
Name:(Pyr³)-Amyloid β-Protein (3-40)
Brand:Bachem
Description:The pyroglutamate-modified amyloid-β peptides derived from Aβ40 and Aβ42 have gained considerable attention as potential key participants in the pathology of Alzheimer’s disease (AD) due to their abundance in AD brain, high aggregation propensity, stability, and cellular toxicity. Aβ40 and 42 can be N-terminally truncated by action of cathepsin B. The cyclization of Glu³ is catalyzed by glutaminyl cyclase. Hence, inhibition of these enzymes could be a therapeutic approach to AD.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:4125.68
Formula:C187H283N51O53S
Purity:97.3%
Color/Form:White
Technical inquiry about: (Pyr³)-Amyloid β-Protein (3-40)
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