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(Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)

CAS: 181477-43-0

Ref. 01-H-4938

1mg
97.00 €Add to cart
5mg
376.00 €Add to cart
Estimated delivery in United States, on Monday 13 Dec 2021

Product Information

Name:
(Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)
Synonyms:
  • (Met186)-Melanoma-Associated ME20 Antigen (185-193) (human, bovine, mouse), (Met186)-Melanocyte Lineage-Specific Antigen GP100 (185-193) (human, bovine, mouse), (Met186)-ME20M/ME20S (185-193) (human, bovine, mouse), (Met186)-ME20-M/ME20-S (185-193) (human, bovine, mouse), (Met186)-95 kDa Melanocyte-Specific Secreted Glycoprotein (185-193) (human, bovine, mouse), Disomotide
  • L-Isoleucyl-L-methionyl-L-alpha-aspartyl-L-glutaminyl-L-valyl-L-prolyl-L-phenylalanyl-L-seryl-L-valine
Description:
Modified sequence of the gp100 epitope gp(209-217) ITDQVPFSV, in which a methionine replaced the natural threonine at position 2, bound to the HLA-A2 molecule with greater affinity than the unmodified peptide and was shown to have an increased ability to generate melanoma-reactive cytotoxic T lymphocytes (CTLs) in vitro when used for sensitization of peripheral blood mononuclear cells. IMDQVPFSV hold promise for the development of novel cancer immunotherapies.
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Chemical properties

Molecular weight:
1034.51067
Formula:
C47H74N10O14S
MDL:
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
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Technical inquiry about: 01-H-4938 (Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)

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