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Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide
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Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide

CAS: 339990-02-2

Ref. 01-H-6138

5mg
67.00 €Add to cart
25mg
247.00 €Add to cart
Estimated delivery in United States, on Wednesday 15 Dec 2021

Product Information

Name:
Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide
Synonyms:
  • iAb5p, Beta-sheet Breaker Peptide biA 5p
  • 10:PN: WO03050139 SEQID: 15 claimed protein
  • 3: PN: WO0134631 PAGE: 35 claimedprotein
  • As 602704
  • Ac-Leu-Pro-Phe-Phe-Asp-Nh2
Description:
The pentapeptide Ac-LPFFD-NH2 (iAb5p) is an analog of product H-4876 with small chemical modifications which enhance its stability against proteolytic degradation. iAb5p acts as a b-sheet breaker peptide and crosses the blood-brain barrier at a higher rate than most proteins and peptides known to be selectively taken up by the brain so that it is assumed that the peptide is being specifically transported to the brain. A significant increase in neuronal survival and decrease in brain inflammation associated with the reduction of amyloid plaques in two different transgenic Alzheimer`s disease (AD) models is additionally reported for iAb5p.
Long term storage:
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Chemical properties

Molecular weight:
678.33771
Formula:
C35H46N6O8
Purity:
> 95%
Color/Form:
White Powder
MDL:
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EINECS:
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Hazard Info

UN Number:
EQ:
Class:
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Forbidden to fly:
Hazard Info:
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