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(Pyr3)-Amyloid b-Protein (3-40)
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(Pyr3)-Amyloid b-Protein (3-40)

CAS: 161818-04-8

Ref. 01-H-7422

1mg
402.00 €Add to cart
0.5mg
231.00 €Add to cart
Estimated delivery in United States, on Tuesday 7 Dec 2021

Product Information

Name:
(Pyr3)-Amyloid b-Protein (3-40)
Description:
The pyroglutamate-modified amyloid-b peptides derived from Ab40 and Ab42 have gained considerable attention as potential key participants in the pathology of Alzheimer's disease (AD) due to their abundance in AD brain, high aggregation propensity, stability, and cellular toxicity. Ab40 and 42 can be N-terminally truncated by action of cathepsin B. The cyclization of Glu3 is catalyzed by glutaminyl cyclase. Hence, inhibition of these enzymes could be a therapeutic approach to AD.
Long term storage:
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Chemical properties

Molecular weight:
4123.0738
Formula:
C187H283N51O53S
Purity:
>95%
Color/Form:
White
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
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Technical inquiry about: 01-H-7422 (Pyr3)-Amyloid b-Protein (3-40)

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